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首页> 外文期刊>Seminars in Gastrointestinal Disease >Diagnosis of esophageal ulcers in acquired immunodeficiency syndrome.
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Diagnosis of esophageal ulcers in acquired immunodeficiency syndrome.

机译：诊断为获得性免疫缺陷综合症的食道溃疡。

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摘要

The esophagus is one of the most common sites of gastrointestinal involvement in human immunodeficiency virus (HIV)-infected patients, with at least 30% of the patients having esophageal symptoms at some point during the course of HIV infection. Esophageal ulcers are commonly caused by infections such as cytomegalovirus (CMV) or may be idiopathic. The clinical presentation of the various causes of esophageal ulcers are similar; therefore, a thorough endoscopic and histological workup is imperative to make a diagnosis and, consequently, to provide appropriate therapy. The widespread use of more effective antiretroviral therapy appears to have led to a decline in gastrointestinal opportunistic disorders in patients with acquired immunodeficiency syndrome (AIDS), including those involving the esophagus. Unfortunately, there are several reports of resistance of HIV-1 to multiple antiretroviral agents, and thus it is possible we will observe an increase in various opportunistic disorders again. The aim of this article is to provide a practical approach to the clinical, endoscopic, and histopathologic evaluation of esophageal ulcers in patients with AIDS.
机译：在感染人类免疫缺陷病毒（HIV）的患者中，食道是胃肠道最常见的部位之一，至少有30％的患者在HIV感染过程中的某个时候出现食道症状。食道溃疡通常由巨细胞病毒（CMV）等感染引起，也可能是特发性的。各种原因引起的食管溃疡的临床表现相似。因此，必须进行彻底的内窥镜和组织学检查以进行诊断，并因此提供适当的治疗方法。广泛使用更有效的抗逆转录病毒疗法似乎已导致患有后天免疫机能丧失综合症（AIDS）的患者（包括食道疾病）的胃肠道机会性疾病减少。不幸的是，有关于HIV-1对多种抗逆转录病毒药物耐药的报道，因此我们有可能再次观察到各种机会性疾病的增加。本文的目的是为艾滋病患者的食道溃疡的临床，内窥镜检查和组织病理学评估提供实用的方法。

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