Retention, dosing, tolerability and patient reported seizure outcome of Zonisamide as only add-on treatment under real-life conditions in adult patients with partial onset seizures: Results of the observational study ZOOM

Hamer Hajo; Baulac Michel; McMurray Rob; Kockelmann Edgar

首页> 外文期刊>Seizure: the journal of the British Epilepsy Association >Retention, dosing, tolerability and patient reported seizure outcome of Zonisamide as only add-on treatment under real-life conditions in adult patients with partial onset seizures: Results of the observational study ZOOM

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Retention, dosing, tolerability and patient reported seizure outcome of Zonisamide as only add-on treatment under real-life conditions in adult patients with partial onset seizures: Results of the observational study ZOOM

机译：ZONIS的保留，剂量，耐受性和患者报告的癫痫发作结局仅是在生活条件下对部分发作的成年患者在现实生活中的附加治疗：ZOOM观察性研究的结果

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Purpose: Zonisamide is licensed for adjunctive therapy for partial-onset seizures with or without secondary generalisation in patients 6 years and older and as monotherapy for the treatment of partial seizures in adult patients with newly diagnosed epilepsy, and shows a favourable pharmacokinetic profile with low interaction potential with other drugs. The aim of the present study was to gather real life data on retention and modalities of zonisamide use when administered as only add-on treatment to a current AED monotherapy in adult patients with partial-onset seizures.

机译：目的：唑尼沙胺已获许可用于6岁及以上患者的部分发作或不继发性全身性发作的辅助治疗，以及单药治疗新诊断的癫痫成年患者的部分发作，并显示出良好的药代动力学特征，且相互作用低与其他药物的潜力。本研究的目的是收集关于部分使用癫痫发作的成人AED单一疗法的附加治疗方案时，唑尼沙胺使用保留和方式的真实生活数据。

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《Seizure: the journal of the British Epilepsy Association》 |2016年第null期|共8页
作者
Hamer Hajo; Baulac Michel; McMurray Rob; Kockelmann Edgar;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Partial-onset seizures; Epilepsy; Zonisamide; Elderly; Retention; Observational study;

机译：部分发作性癫痫;癫痫;唑尼沙胺;老年人;Re留;观察研究;

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1. Retention, dosing, tolerability and patient reported seizure outcome of Zonisamide as only add-on treatment under real-life conditions in adult patients with partial onset seizures: Results of the observational study ZOOM [J] . Hamer Hajo, Baulac Michel, McMurray Rob, Seizure: the journal of the British Epilepsy Association . 2016,第Null期

机译：ZONIS的保留，剂量，耐受性和患者报告的癫痫发作结局仅是在生活条件下对部分发作的成年患者在现实生活中的附加治疗：ZOOM观察性研究的结果
2. Pregabalin add-on treatment in patients with partial seizures: a novel evaluation of flexible-dose and fixed-dose treatment in a double-blind, placebo-controlled study. [J] . Elger CE, Brodie MJ, Anhut H, Epilepsia: Journal of the International League against Epilepsy . 2005,第12期

机译：普瑞巴林附加治疗部分发作的患者：一项双盲，安慰剂对照研究中对灵活剂量和固定剂量治疗的新颖评估。
3. Dose-response population analysis of levetiracetam add-on treatment in refractory epileptic patients with partial onset seizures. [J] . Snoeck E, Stockis A Epilepsy research . 2007,第3期

机译：左乙拉西坦追加治疗部分发作性难治性癫痫患者的剂量反应人群分析。
4. Impact of Dose Received by the Oral Cavity on Patient Reported Outcomes in the Setting of Deescalated Radiotherapy Treatment [D] . Fuquay, Andrew T. 2020

机译：口腔对患者口腔接受的影响报告了欺骗放疗治疗的结果
5. Evaluation of safety and efficacy of zonisamide in adult patients with partial generalized and combined seizures: an open labeled noncomparative observational Indian study [O] . Amitabh Dash, Sangeeta Ravat, Avathvadi Venkatesan Srinivasan, 2016

机译：zonisamide在部分全身和合并发作的成年患者中的安全性和疗效评估：一项开放性非对照性观察性印度研究
6. Retention, dosing, tolerability and patient reported seizure outcome of Zonisamide as only add-on treatment under real-life conditions in adult patients with partial onset seizures: Results of the observational study ZOOM [O] . Hamer Hajo, Baulac Michel, McMurray Rob, 2016

机译：ZONIS的保留，给药，耐受性和患者报告的癫痫发作结局仅是在生活条件下对部分发作的成年患者在现实生活中的附加治疗：ZOOM观察性研究的结果

Retention, dosing, tolerability and patient reported seizure outcome of Zonisamide as only add-on treatment under real-life conditions in adult patients with partial onset seizures: Results of the observational study ZOOM

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