• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Seminars in neurology >Update on paraneoplastic and autoimmune disorders of the central nervous system.
【24h】

Update on paraneoplastic and autoimmune disorders of the central nervous system.

机译：中枢神经系统副肿瘤和自身免疫性疾病的更新。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Although the discovery of antineuronal antibodies has facilitated the diagnosis of paraneoplastic neurologic disorders, the recognition and treatment of these disorders remain a challenge. Some antibodies are more syndrome-specific than others, and some syndromes suggest a paraneoplastic etiology more frequently than others. Because some antineuronal antibodies may occur in cancer patients without paraneoplastic neurologic disorders, their detection does not necessarily imply that a neurologic disorder is paraneoplastic. Moreover, there is an emerging group of encephalitides that appear to be mediated by antibodies against cell surface or synaptic proteins, may occur with or without tumor association, and are responsive to treatment. This review analyzes the immune responses associated with paraneoplastic and nonparaneoplastic disorders of the central nervous system, and the main clinical features and response to treatment.
机译：尽管抗神经元抗体的发现促进了副肿瘤性神经系统疾病的诊断，但是这些疾病的识别和治疗仍然是一个挑战。一些抗体比其他抗体更具综合症特异性，并且某些综合症比其他抗体更常提示副肿瘤病因。因为一些抗神经元抗体可能会在没有副肿瘤性神经系统疾病的癌症患者中发生，所以对其进行检测并不一定意味着神经系统疾病是副肿瘤性的。而且，出现了一组新兴的脑肽，它们似乎是由针对细胞表面或突触蛋白的抗体介导的，可能在有或没有肿瘤关联的情况下发生，并对治疗有反应。这篇综述分析了与中枢神经系统副肿瘤和非副肿瘤疾病相关的免疫反应，以及主要的临床特征和对治疗的反应。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号