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首页> 外文期刊>Seizure: the journal of the British Epilepsy Association >Maternal and obstetric outcome of women with epilepsy.
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Maternal and obstetric outcome of women with epilepsy.

机译：癫痫妇女的产妇和产科预后。

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Medical professionals and public are concerned about the complications of pregnancy and delivery in women with epilepsy (WWE). PURPOSE: Our aim was to prospectively ascertain occurrence of these complications in a cohort of WWE enrolled in a pregnancy registry. METHODS: All complications during pregnancy, delivery and first 48 h of postpartum period were recorded according to the registry protocol. This data were compared with similar statistics (for women without epilepsy) from a large teaching hospital. RESULTS: Between April 1998 and March 2005, there were 643 completed pregnancies in this registry. (Mean age 25.7+/-4.43 years; generalized epilepsy 46%; localization related epilepsy 54%; primigravida 53%.) Their complications are compared with those of 18,272 pregnancies managed in the teaching hospital (in parentheses). Spontaneous abortions 4.2% (2.38%); medical termination of pregnancies 2.64% (7.71%); anemia 0.62% (0.22%); gestational diabetes 1.56% (3.09%); pregnancy induced hypertension 3.89% (6.45%); antepartum hemorrhage 0.93% (1.64%); preterm labor 1.87% (6.12%); obstructed labor 0.62% (3%); cesarean section 33.4% (29.5%); assisted delivery 2.8% (2.68%); postpartum hemorrhage 0.31% (0.64%); peripartum seizures 1.4% (0.04%); intrauterine death 1.56% (2.2%); fibroid uterus or ovarian cyst 2.33% (0.53%); other medical illness 2.5% (2.15%); TORCH infection 0.31% (0.01%); birth weight <2.0 kg 4.19% (7.66%). CONCLUSIONS: There was no significant increase in the risk of complications of pregnancy or delivery except for spontaneous abortions, anemia, ovarian cyst, fibroid uterus, and seizures in the peripartum period which were more frequent in WWE. Frequency of cesarean section is not increased in WWE. There is no undue risk to pregnancy and childbirth in most WWE.
机译：医疗专业人员和公众都对癫痫妇女（WWE）的妊娠和分娩并发症感到担忧。目的：我们的目的是前瞻性地确定参加妊娠登记的WWE队列中这些并发症的发生。方法：根据登记方案记录妊娠，分娩和产后前48小时的所有并发症。将该数据与一家大型教学医院的类似统计数据（无癫痫妇女）进行了比较。结果：从1998年4月到2005年3月，该登记处完成了643例怀孕。 （平均年龄25.7 +/- 4.43岁;全身性癫痫46％;定位相关性癫痫54％;初生妊娠53％。）将其并发症与教学医院管理的18272例孕妇的并发症进行比较（在括号中）。自发流产4.2％（2.38％）;医疗终止怀孕2.64％（7.71％）;贫血0.62％（0.22％）;妊娠糖尿病1.56％（3.09％）;妊娠高血压病3.89％（6.45％）;产前出血0.93％（1.64％）;早产1.87％（6.12％）;受阻劳动0.62％（3％）;剖宫产33.4％（29.5％）;辅助分娩2.8％（2.68％）;产后出血0.31％（0.64％）;围产期癫痫发作1.4％（0.04％）;宫内死亡1.56％（2.2％）;子宫肌瘤或卵巢囊肿2.33％（0.53％）;其他内科疾病2.5％（2.15％）;火炬感染0.31％（0.01％）;出生体重<2.0千克为4.19％（7.66％）。结论：除了自然流产，贫血，卵巢囊肿，子宫肌瘤和围产期癫痫发作（在WWE中更为频繁）外，妊娠或分娩并发症的风险没有显着增加。在WWE中，剖宫产的频率没有增加。在大多数WWE中，没有怀孕和分娩的不适当风险。

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