首页> 外文期刊>Seminars in cancer biology >Cancer immunotherapy with chemoattractant peptides.
【24h】

Cancer immunotherapy with chemoattractant peptides.

机译:趋化肽进行癌症免疫治疗。

获取原文
获取原文并翻译 | 示例
           

摘要

The chemokine/chemokine receptor network is an essential part of an intricate system of immunosurveillance and homeostasis, it promotes or suppresses neovascularization, affects and regulates directly or indirectly growth and metastasis of malignant cells. Numerous studies have been conducted to harness this network as therapeutic agents for cancer to redress the chemokine balance and control angiogenesis and tumour growth and metastasis. Second generation of immunotherapeutics and chemoattractant-based vaccines use chemokines and chemoattractant peptides to elicit antitumor immunity by a specific targeting and modulating subsets of effector leukocytes, including professional antigen presenting cells.
机译:趋化因子/趋化因子受体网络是复杂的免疫监视和体内平衡系统的重要组成部分,它促进或抑制新血管形成,直接或间接影响和调节恶性细胞的生长和转移。已经进行了大量研究以利用该网络作为癌症的治疗剂,以解决趋化因子的平衡并控制血管生成以及肿瘤的生长和转移。第二代基于免疫疗法和化学引诱剂的疫苗使用趋化因子和化学引诱剂肽通过特异性靶向和调节效应白细胞(包括专业抗原呈递细胞)的子集来引发抗肿瘤免疫力。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号