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Vasomotor symptoms: viewpoint from the Indian subcontinent and management of a common menopausal problem.

机译:血管舒缩症状:印度次大陆的观点和常见的更年期问题的处理。

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摘要

Vasomotor symptoms (VMS) are recognized to adversely affect the quality of life. The prevalence and the magnitude of VMS may vary across populations. Although a natural regression of VMS may be expected over a period of time, it remains the most common of symptoms for which women seek help. Menopausal hormone therapy (MHT) is currently the only treatment approved by the Food and Drug Administration that has shown uniform benefit in the management of VMS. In clinical situations when estrogen is or may be contraindicated, a finite number of alternative options, including use of neuroactive agents (SSRIs, SSNRs, and gabapentin), lifestyle changes, and nonprescription remedies such as phytoestrogens and black cohosh have been shown to provide relief, albeit with mixed results and questionable safety. Existing data identify an ethnic variation in the degree and frequency of VMS of aging; in this latter context, the Asian woman's perspective is dominantly conveyed from the perspective of Chinese and Japanese ethnicities, whereas data regarding the magnitude of burden of VMS in the postmenopausal women from other Asian ethnicities and races are sparse. This article reviews the symptoms and relates that VMS are of significant concern for the aging Asian women.
机译:血管舒缩症状(VMS)被认为会对生活质量产生不利影响。 VMS的患病率和严重程度可能因人群而异。尽管VMS可能会在一段时间内自然退化,但它仍然是妇女寻求帮助的最常见症状。更年期激素疗法(MHT)是目前美国食品与药物管理局(FDA)批准的唯一在VMS管理中显示出统一获益的疗法。在雌激素禁忌的临床情况下,有限的替代选择,包括使用神经活性剂(SSRI,SSNR和加巴喷丁),生活方式的改变以及非处方药(如植物雌激素和黑升麻)已显示出缓解作用。 ,尽管结果复杂且安全性令人怀疑。现有数据表明,VMS老化程度和频率存在种族差异;在后一种情况下,从中国和日本种族的角度主要传达了亚洲妇女的观点,而关于来自其他亚洲种族和种族的绝经后妇女的VMS负担程度的数据很少。本文对这些症状进行了回顾,并指出VMS是老化的亚洲女性的重要关注点。

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