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首页> 外文期刊>Chembiochem: A European journal of chemical biology >A Half-Century of Neurotrasmitter Research:Impact on Neurology and Psychiatry(Nobel Lecture)
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A Half-Century of Neurotrasmitter Research:Impact on Neurology and Psychiatry(Nobel Lecture)

机译：半个世纪的神经递质研究：对神经病学和精神病学的影响（诺贝尔讲座）

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My encounter with dopamine followed an incredible sequence of fortunate events.Ihad been working on calcium metabolism using radioactive isotopes,which had then just become commercially available.This work had resulted in m doctoral thisis in 1951 and a series of subsequent papers,including two doctoral theses by students of mine.Our results had become somewhat visible interntionally,reslting,for example,in an invitation to a Gordon Conference in New England in 1955.The reason why I left this fidld of research was that,in connection with a competition for an associate professorship in pharmacol-ogy,the expert committee let me know that in their opinion calcium metabolism did not occupy a central position in pharmacology,Ithereford turned to professor Sune Bergstron(Figure1),who was at that time head of the Department of physiological Chemistry at the University of Lund,Sweden .This department was located in the same building as our Pharma-cologyDepartment.professor Bergstrom had already been very helpful in several instances when Ihad had a professional problem of some kind .Incidentally,Dr. Bengt Samuelsson was at that time working with Professor Bergstrom in the same department .Thus,the three Swedes who were to become Nobel laureates in the period 1980-2000 happened to be working under the same roof for a rew years.
机译：我与多巴胺的相遇发生了一系列令人难以置信的不幸事件。我一直在使用放射性同位素进行钙代谢研究，后来这种钙才刚刚商业化。这项工作在1951年获得了博士学位，随后发表了一系列论文，其中包括两篇博士论文。我们的研究结果在国际上已经有些明显，例如，应1955年在新英格兰举行的戈登会议的邀请。我之所以离开这一研究领域的原因是，药理学副教授，专家委员会让我知道，他们认为钙代谢在药理学中并不占中心地位，伊特尔福德求助​​于当时担任生理学系主任的苏尼·贝格斯特龙教授（图1）。瑞典隆德大学化学系。该系与我们的药物生物学系位于同一栋大楼内。伯格斯特罗姆教授已经在某些情况下，当我遇到某种专业问题时，我非常乐于助人。 Bengt Samuelsson当时在同一部门与Bergstrom教授一起工作。因此，在1980-2000年期间成为诺贝尔奖获得者的三位瑞典人恰好在同一屋檐下工作了数年。

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