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首页> 外文期刊>Skeletal radiology >Microscopic correlation of radiographically disparate appearing well differentiated osteosarcoma.
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Microscopic correlation of radiographically disparate appearing well differentiated osteosarcoma.

机译：影像学上相异的高分化骨肉瘤的微观相关性。

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摘要

Well differentiated (low grade) osteosarcomas are often unrecognized and inadequately treated. We report on a patient with a well differentiated osteosarcoma of the tibia that radiographically presented with two strikingly dissimilar appearing juxtaposed lesions. Proximally, the lesion was sclerotic, and distally, osteolytic. The distal lytic half of the lesion showed focal cortical disruption on MR imaging. Microscopic correlation of the resected specimen suggested that the sclerotic component of the lesion had more fibrous dysplasia-like tissue with fewer features of well differentiated osteosarcoma, and the lytic component, features suggestive of well differentiated osteosarcoma. We believe this microscopic interpretation explains the disparate radiographic appearance as all belonging to well differentiated osteosarcoma with varying amounts of fibrous dysplasia-like tissue rather than the development of well differentiated osteosarcoma in fibrous dysplasia.
机译：高分化（低度）骨肉瘤通常未被识别且治疗不充分。我们报道了一名患者的胫骨高分化骨肉瘤，影像学表现为两个明显不同的并列病变。病灶近端是硬化的，远端是溶骨的。病变的远端溶解一半在MR成像上显示局灶性皮质破坏。切除标本的显微相关性表明，病变的硬化成分具有更多的纤维异常增生样组织，具有较少分化的骨肉瘤特征，而溶解成分则暗示了分化良好的骨肉瘤特征。我们相信这种微观解释解释了不同的放射学表现，因为它们全部属于分化良好的骨肉瘤，具有数量不同的纤维异常增生样组织，而不是纤维分化异常的高分化骨肉瘤的发展。

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