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首页> 外文期刊>Skin research and technology: official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) >Application of optical coherence tomography in non-invasive characterization of skin vascular lesions.
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Application of optical coherence tomography in non-invasive characterization of skin vascular lesions.

机译：光学相干断层扫描技术在皮肤血管病变的非侵入性表征中的应用。

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摘要

BACKGROUND: Optical coherence tomography (OCT) is a new non-invasive approach for real-time in vivo tissue characterization. A promising use of OCT can be the assessment of the architecture of lesions with some degree of inhomogeneities, such as vascular lesions. Knowledge of the size and depth of the vascular structures can be useful for the diagnosis and for choosing the best treatment. OBJECTIVE: The purpose of this study was to investigate a series of vascular lesions by means of OCT in order to obtain new insights into the non-invasive, pre-operative analysis of these lesions. METHODS: Seven vascular lesions were included in the study. Histopathological diagnosis showed two haemangiomas and one haemolymphangioma; the remaining four cases were classified as haemangiomas on the basis of their clinical appearance. RESULTS: In all lesions, OCT analysis was able to visualize different areas of the lesion from the horny layer to the dermis showing a clear image of the vascular proliferation. Specifically, oval to roundish signal-poor areas sharply demarcated by a surrounding signal-rich layer were observed in good correlation with histopathology. CONCLUSION: The analysis of vascular lesions by OCT provides a new insight into non-invasive diagnosis and can be helpful in the selection of the most appropriate treatment.
机译：背景：光学相干断层扫描（OCT）是用于实时体内组织表征的一种新的非侵入性方法。 OCT的有前途的用途可以是评估具有一定程度不均匀性的病变（例如血管病变）的结构。了解血管结构的大小和深度对于诊断和选择最佳治疗很有用。目的：本研究的目的是通过OCT研究一系列血管病变，以期获得对这些病变的非侵入性术前分析的新见解。方法：该研究包括七个血管病变。组织病理学诊断为2例血血管瘤和1例血淋巴管瘤。其余4例根据其临床表现被分类为血管瘤。结果：在所有病变中，OCT分析能够可视化病变区域从角质层到真皮的不同区域，显示出清晰的血管增生图像。具体地，观察到由周围的富含信号的层清晰地划定的椭圆形至圆形的信号贫乏区域与组织病理学具有良好的相关性。结论：OCT分析血管病变可为非侵入性诊断提供新的见解，并有助于选择最合适的治疗方法。

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