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The colour of blood in skin: a comparison of Allen's test and photonics simulations.

机译:皮肤中的血液颜色:艾伦测试与光子模拟的比较。

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BACKGROUND: The colour of the skin reflects many physiological and pathological states of an individual. Usually, the skin colour is examined by the bare eye alone. Several scaling systems have been developed to quantify the sensory evaluation of skin colour. In this work, the reflectance of the skin is measured directly using an objective instrument. Haemoglobin inside the dermal circulation is one of the key factors of skin colour and it also has a major role in the appearance of many skin lesions and scars. To quantitatively measure and analyse such conditions, the relation between the skin colour and the haemoglobin concentration in the skin needs to be resolved. METHODS: To examine the effect of blood concentration on the skin colour, five Allen's tests were performed on 20 persons. The skin colour change was measured using a spectrophotometer by changing the blood concentration by the Allen's test. Light interaction with the skin was simulated with a Monte Carlo model, tuning the blood concentration parameter until the simulated and the measured spectra matched, yielding the relationship between the skin colour and the blood concentration. RESULTS: The simulation produced spectra similar to those measured. The change in the blood concentration in the simulation model and in the skin produced changes similar to the spectra. The reflectance of the skin was found to be a nonlinear function of the blood concentration. CONCLUSION: The relationship found between skin colour and blood concentration makes it possible to quantify those skin conditions expressed by blood volume better than plain colour.
机译:背景:皮肤的颜色反映了个体的许多生理和病理状态。通常,仅通过裸眼检查肤色。已经开发了几种定标系统以量化皮肤颜色的感官评估。在这项工作中,使用物镜直接测量皮肤的反射率。皮肤循环内的血红蛋白是皮肤颜色的关键因素之一,并且在许多皮肤损伤和疤痕的出现中也起着重要作用。为了定量地测量和分析这种状况,需要解决皮肤颜色与皮肤中血红蛋白浓度之间的关系。方法:为检查血液浓度对皮肤颜色的影响,对20人进行了五次艾伦(Allen's)测试。使用分光光度计通过艾伦氏测试通过改变血液浓度来测量皮肤颜色变化。用蒙特卡洛模型模拟与皮肤的光相互作用,调整血液浓度参数,直到模拟的和测量的光谱匹配为止,得出皮肤颜色与血液浓度之间的关系。结果:模拟产生的光谱类似于所测得的光谱。模拟模型和皮肤中血液浓度的变化产生类似于光谱的变化。发现皮肤的反射率是血液浓度的非线性函数。结论:皮肤颜色与血液浓度之间的关系使定量由血液量表示的皮肤状况比纯色更好。

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