首页> 外文期刊>Spinal cord: the official journal of the International Medical Society of Paraplegia >Electrical stimulation-evoked resistance exercise therapy improves arterial health after chronic spinal cord injury.
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Electrical stimulation-evoked resistance exercise therapy improves arterial health after chronic spinal cord injury.

机译:电刺激诱发的阻力运动疗法可改善慢性脊髓损伤后的动脉健康。

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STUDY DESIGN: Repeated measures training intervention. OBJECTIVES: To evaluate the effects of neuromuscular electrical stimulation (NMES)-induced resistance exercise therapy on lower extremity arterial health in individuals with chronic, complete spinal cord injury (SCI). We define "arterial health" using three surrogate markers: (a) resting diameter, (b) flow-mediated dilation (FMD), and (c) arterial range. SETTING: Department of Kinesiology, University of Georgia, USA. METHODS: We assessed five 36+/-5-year-old male individuals with chronic, complete SCI before, during, and after 18 weeks of training. The quadriceps femoris muscle group of both legs were trained twice a week with 4 x 10 repetitions of unilateral, dynamic knee extensions. The health of the posterior tibial artery was assessed using a B-mode ultrasound unit equipped with a high-resolution video capture device. Proximal occlusion was used to evoke ischemia for 5 min and then for 10 min. FMD was calculated using the peak diameter change (above rest) following 5 min occlusion. Arterial range was calculated using minimum (during occlusion) and maximum diameters (post 10 min occlusion). Hierarchical linear modeling accounted for the nested (repeated measures) experimental design. RESULTS: FMD improved from 0.08+/-0.11 mm (2.7%) to 0.18+/-0.15 mm (6.6%) (P=0.004), and arterial range improved from 0.36+/-0.28 to 0.94+/-0.40 mm (P=0.001), after 18 weeks of training. Resting diameter did not significantly change. CONCLUSIONS: Home-based, self-administered NMES resistance exercise therapy consisting of 80 contractions/week improved FMD and arterial range. This provides evidence that resistance exercise therapy can improve arterial health after SCI, which may reduce the risk of future cardiovascular disease.
机译:研究设计:重复措施培训干预措施。目的:评估神经肌肉电刺激(NMES)诱导的阻力运动疗法对慢性,完全性脊髓损伤(SCI)患者下肢动脉健康的影响。我们使用三个替代标记定义“动脉健康”:(a)静息直径,(b)流量介导的扩张(FMD),以及(c)动脉范围。单位:美国乔治亚大学运动学系。方法:我们评估了五名36 +/- 5岁的男性,他们在训练前,训练中和训练后均患有慢性完全性SCI。每周两次训练股四头肌股四头肌,每组重复进行4 x 10次单侧动态膝关节伸展训练。使用配备高分辨率视频捕获设备的B型超声仪评估胫骨后动脉的健康状况。近端阻塞用于引起缺血5分钟,然后持续10分钟。使用5分钟闭塞后的峰直径变化(静止以上)来计算FMD。使用最小(阻塞时)和最大直径(阻塞10分钟后)计算动脉范围。分层线性建模说明了嵌套(重复测量)实验设计。结果:FMD从0.08 +/- 0.11 mm(2.7%)改善至0.18 +/- 0.15 mm(6.6%)(P = 0.004),动脉范围从0.36 +/- 0.28 mm改善至0.94 +/- 0.40 mm( P = 0.001),经过18周的训练。静止直径没有明显变化。结论:家庭自我管理的NMES抵抗运动疗法包括每周80次收缩,改善FMD和动脉范围。这提供了抵抗运动疗法可以改善SCI后的动脉健康的证据,这可以降低将来发生心血管疾病的风险。

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