...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Spine >Primary and secondary osteoporosis' incidence of subsequent vertebral compression fractures after kyphoplasty.
【24h】

Primary and secondary osteoporosis' incidence of subsequent vertebral compression fractures after kyphoplasty.

机译：后凸成形术后继发椎体压缩性骨折的原发性和继发性骨质疏松症的发生率。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

STUDY DESIGN: Retrospective review of prospective database. OBJECTIVES: Define the incidence of adjacent and remote fractures after kyphoplasty vertebral augmentation, and identify vulnerable subpopulations at increased risks. SUMMARY OF BACKGROUND DATA: Painful osteoporotic compression fractures can be effectively treated with methyl methacrylate vertebral augmentation, but the effect of intervention on the generation of future remote and adjacent fractures has not been identified. No paper has analyzed the association of long-term steroid use to subsequent compression fractures. METHODS: A total of 175 patients were treated for compression fractures, from October 1999 to November 2001, 60 patients were excluded due to insufficient follow-up (less than 3 months) or malignancy related fracture. The remaining 115 patients' charts and radiographs were then individually analyzed. New fractures were identified based on changes from baseline imaging studies (). Demographic information, vertebral levels treated, adjacent fractures, and remote fractures underwent statistical analyzed (P < 0.05). RESULTS: A total of 225 vertebral bodies were treated in 115 patients using the kyphoplasty technique; of those, 26 patients developed 34 subsequent compression fractures. The mean follow-up was 11 months (range, 3-33 months). The incidence of subsequent fracture per procedure per kyphoplasty was 15.1% (34 of 225), overall incidence per patient was 22.6% (26 of 115). There were 80 patients with primary osteoporosis and 35 patients with secondary steroid-induced osteoporosis. These populations were similar in terms of demographics, single or multiple sites, along with two or three adjacent levels treated. Seventeen of the 26 (65%) patients with subsequent fracture had secondary steroid-induced osteoporosis, while only 9 of the 26 (35%) patients had primary osteoporosis. Therefore, the incidence of post-kyphoplasty VCF in the primary osteoporotic patient was 11.25% (9 of 80) and the incidence in the steroid-induced osteoporotic patient was 48.6% (17 of 35). This increased fracture rate in the steroid-dependent patients was significant (P < 0.0001), along with adjacent fractures (12 of 19 on steroids, P = 0.0009), and remote fractures (7 of 9 on steroids, P = 0.027). CONCLUSIONS: Steroid-induced compression fractures appear to have an increased incidence of subsequent fractures after the kyphoplasty procedure. The kyphoplasty protocol with concurrent medical osteoporotic regimen does not appear to increase, and may serve to reduce, the incidence of remote and adjacent fractures for primary osteoporotic fractures.
机译：研究设计：回顾性前瞻性数据库。目的：确定椎体后凸成形术后邻近和远端骨折的发生率，并确定风险增加的易受伤害的亚人群。背景资料摘要：甲基丙烯酸甲酯椎体隆突可以有效治疗疼痛性骨质疏松性压缩性骨折，但尚未发现干预措施对未来远距离和邻近骨折产生的影响。没有论文分析长期使用类固醇与随后的压迫性骨折的关系。方法：1999年10月至2001年11月，共收治175例压缩性骨折患者，由于随访不足（少于3个月）或恶性肿瘤相关性骨折而被排除在外。然后分别分析其余115位患者的图表和X射线照片。根据基线影像学研究的变化确定了新的骨折（）。对人口统计学信息，治疗的椎骨水平，邻近骨折和远端骨折进行统计学分析（P <0.05）。结果：采用后凸成形术治疗了115例患者中总共225具椎体。其中26例患者随后发生了34例压迫性骨折。平均随访时间为11个月（范围3-33个月）。每次后凸成形术每个手术后继骨折的发生率为15.1％（225次中的34次），每位患者的总发生率为22.6％（115次中的26次）。有80例原发性骨质疏松症患者和35例继发类固醇诱导的骨质疏松症患者。这些人口在人口统计，单个或多个地点以及两个或三个相邻水平的方面都相似。在随后骨折的26位患者中，有十七位（65％）患有继发性类固醇诱发的骨质疏松症，而在26位患者（35％）中，只有9位患有原发性骨质疏松症。因此，原发性骨质疏松患者的后凸成形术后VCF的发生率为11.25％（80例中​​的9例），类固醇诱导的骨质疏松患者的发生率为48.6％（35例中的17例）。在类固醇依赖型患者中，骨折率增加（P <0.0001），以及邻近的骨折（类固醇19例中有12例，P = 0.0009）和远端骨折（类固醇9例中有7例，P = 0.027）。结论：椎体后凸成形术后，类固醇诱发的压迫性骨折后继骨折的发生率增加。并发医疗性骨质疏松方案的后凸成形术方案似乎并未增加，并且可能有助于减少原发性骨质疏松性骨折的远端和邻近骨折的发生率。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号