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首页> 外文期刊>Spine >Efficacy and safety of percutaneous sacroplasty for painful osteoporotic sacral insufficiency fractures: a prospective, multicenter trial.
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Efficacy and safety of percutaneous sacroplasty for painful osteoporotic sacral insufficiency fractures: a prospective, multicenter trial.

机译：经皮sa囊置换术治疗疼痛性骨质疏松性ac骨功能不全骨折的疗效和安全性：一项前瞻性，多中心试验。

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STUDY DESIGN: A prospective observational cohort study of consecutive osteoporotic patients with sacral insufficiency fractures (SIFs). OBJECTIVE: Assess the safety and efficacy of sacroplasty in treating osteoporotic SIFs. SUMMARY OF BACKGROUND DATA: SIFs can cause low back pain in osteoporotic patients. Symptomatic improvement may require up to 12 months. Treatment includes limited weight-bearing and bed rest, oral analgesics, and sacral corsets. Significant mortality and morbidity are associated with pelvic insufficiency fractures. Percutaneous sacroplasty is an alternative treatment for SIF patients, and initial reports have documented its safe and effective performance. Yet, follow-up intervals have been short, and study cohorts small precluding definitive assessment of sacroplasty's safety and efficacy. METHODS: Baseline Visual Analogue Scale (VAS), analgesic usage, and duration of symptoms were recorded. Subsequent VAS ratings were assessed at 30 minutes and at 2, 4, 12, 24, and 52 weeks postprocedure. Analgesic usage and patient satisfaction were assessed at final follow-up. Each procedure was performed under intravenous conscious sedation using fluoroscopy. Two bone trochars were inserted between the sacral foramen and sacroiliac joint through which 2 to 3 mL of polymethylmethacrylate was injected. RESULTS: Thirty-seven patients, 27 females, were treated. Mean age was 76.6 years, and mean symptom duration was 34.4 days. All patients were available at each follow-up interval except 1 patient who died due to unrelated pulmonary disease before the 4-week follow-up. The mean VAS score at baseline was 7.7 and 3.2 within 30 minutes, and 2.1 at 2, 1.7 at 4, 1.3 at 12, 1.0 at 24, and 0.7 at 52 weeks postprocedure. Improvement at each interval and overall was statistically significant using the Wilcoxon Rank Sum Test. One case of transient S1 radiculitis was encountered. CONCLUSIONS: Sacroplasty appears to be a safe and effective treatment for painful SIF. The rate of improvement is rapid and sustained through 1 year.
机译：研究设计：前瞻性观察队列研究连续consecutive骨功能不全骨折（SIFs）的骨质疏松患者。目的：评估cro囊成形术治疗骨质疏松性SIF的安全性和有效性。背景数据摘要：SIF可以在骨质疏松症患者中引起腰痛。症状改善可能需要长达12个月的时间。治疗包括有限的负重和卧床休息，口服止痛药和骨紧身胸衣。大量的死亡率和发病率与骨盆功能不全骨折有关。经皮sa囊置换术是SIF患者的另一种治疗方法，初步报告已证明其安全有效的表现。然而，随访时间间隔很短，研究队列很小，因此无法确定sa囊成形术的安全性和有效性。方法：记录基线视觉模拟量表（VAS），止痛药的使用以及症状的持续时间。在手术后30分钟，2、4、12、24和52周评估随后的VAS评分。在最后的随访中评估了镇痛剂的使用和患者的满意度。使用荧光检查法在静脉内有意识的镇静作用下进行每种手术。将两个for骨插入char骨孔和关节之间，通过该骨注射2至3 mL聚甲基丙烯酸甲酯。结果：治疗了37例患者，其中女性为27例。平均年龄为76.6岁，平均症状持续时间为34.4天。所有患者均在每个随访时间间隔获得，除了1名在4周随访之前因无关的肺部疾病死亡的患者。术后30分钟内，基线时的VAS平均得分分别为7.7和3.2，第2、2.1、1.7、4、1.3、12、1.0、24和52周时的平均评分分别为2.1、2.1和0.7。使用Wilcoxon秩和检验，每个时间间隔和总体上的改善在统计学上都是显着的。遇到一例短暂性S1神经根炎。结论：cro囊置换术似乎是治疗疼痛性SIF的一种安全有效的方法。改善速度很快并且持续了1年。

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