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首页> 外文期刊>Modern rheumatology >Functional somatic syndrome: how it could be relevant to rheumatologists.
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Functional somatic syndrome: how it could be relevant to rheumatologists.

机译：功能性躯体综合症：与风湿病学家有何关系。

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摘要

Functional somatic syndrome (FSS) is defined as a group of related syndromes characterized more by symptoms, suffering, and disability than by structural or functional abnormality. The diagnostic criteria and/or symptoms of FSS often overlap, and co-morbidity is commonly found among the diseases of FSS. For example, patients with irritable bowel syndrome often suffer from chronic pain, and a high percentage of co-morbidity can be found with fibromyalgia. Accumulating evidence indicates the presence of visceral and somatic hyperalgesia in FSS as a common feature, and the central sensitization mechanism has been suggested to play an important role in the pathophysiology of FSS. In the present article, the authors introduce the concept of FSS focusing on its possible relevance to rheumatology in terms of pain perception. A possible implication of mast cells and proteinase-activated receptor-2 (PAR-2) in FSS is also reviewed.
机译：功能性躯体综合症（FSS）被定义为一组相关的综合症，其特征更多在于症状，痛苦和残疾，而不是结构或功能异常。 FSS的诊断标准和/或症状经常重叠，并且在FSS的疾病中常见合并症。例如，肠易激综合症患者经常患有慢性疼痛，并且纤维肌痛可导致很高的合并症。越来越多的证据表明，FSS内脏和躯体痛觉过敏的存在是其共同特征，并且已提出中枢敏化机制在FSS的病理生理中起重要作用。在本文中，作者介绍了FSS的概念，着重介绍了FSS在疼痛感方面与风湿病的可能相关性。还对肥大细胞和蛋白酶激活受体2（PAR-2）在FSS中的可能意义进行了综述。

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