...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Stress: the international journal on the biology of stress >Stress in cynomolgus monkeys (Macaca fascicularis) subjected to long-distance transport and simulated transport housing conditions.
【24h】

Stress in cynomolgus monkeys (Macaca fascicularis) subjected to long-distance transport and simulated transport housing conditions.

机译：食蟹猴（Macaca fascicularis）的应力在远距离运输和模拟运输条件下均受到影响。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The stress associated with transportation of non-human primates used in scientific research is an important but almost unexplored part of laboratory animal husbandry. The procedures and routines concerning transport are not only important for the animals' physical health but also for their mental health as well. The transport stress in cynomolgus monkeys (Macaca fascicularis) was studied in two experiments. In Experiment 1, 25 adult female cynomolgus monkeys were divided into five groups of five animals each that received different diets during the transport phase of the experiment. All animals were transported in conventional single animal transport cages with no visual or tactile contact with conspecifics. The animals were transported by lorry for 24 h at ambient temperatures ranging between 20 degrees C and 35 degrees C. Urine produced before, during and after transport was collected and analysed for cortisol by enzyme-linked immunosorbent assay (ELISA). All monkeys exhibited a significant increase in cortisol excretion per time unit during the transport and on the first day following transport.Although anecdotal reports concerning diet during transport, including the provision of fruits and/or a tranquiliser, was thought likely to influence stress responses, these were not corrobated by the present study. In Experiment 2, behavioural data were collected from 18 cynomolgus macaques before and after transfer from group cages to either single or pair housing, and also before and after a simulated transport, in which the animals were housed in transport cages. The single housed monkeys were confined to single transport cages and the pair housed monkeys were kept in their pairs in double size cages. Both pair housed and singly housed monkeys showed clear behavioural signs of stress soon after their transfer out of their group cages.However, stress-associated behaviours were more prevalent in singly housed animals than in pair housed animals, and these behaviours persisted for a longer time after the simulated transport housing event than in the pair housed monkeys. Our data confirm that the transport of cynomolgus monkeys is stressful and suggest that it would be beneficial for the cynomolgus monkeys to be housed and transported in compatible pairs from the time they leave their group cages at the source country breeding facility until they arrive at their final laboratory destination in the country of use.
机译：与科学研究中使用的非人类灵长类动物的运输相关的压力是实验室动物饲养的重要但几乎未开发的部分。有关运输的程序和例程不仅对动物的身体健康很重要，对他们的心理健康也很重要。在两个实验中研究了食蟹猴（Macaca fascicularis）的运输应激。在实验1中，将25只成年雌性食蟹猴分为五组，每组五只动物，在实验的运输阶段接受不同的饮食。所有动物均在常规的单个动物运输笼中运输，没有视觉上或触觉上与同种动物接触。通过卡车在环境温度20摄氏度至35摄氏度之间将动物运输24小时。收集运输之前，期间和之后产生的尿液，并通过酶联免疫吸附测定（ELISA）分析皮质醇。在运输过程中和运输后的第一天，所有猴子的单位时间内皮质醇排泄量均显着增加。尽管有关运输过程中饮食的轶事报道，包括提供水果和/或镇静剂，都可能影响应激反应，这些都没有得到本研究的证实。在实验2中，从群笼转移到单笼或成对笼之前和之后，以及在模拟运输之前和之后，从18只食蟹猕猴收集了行为数据，在模拟运输中将动物圈养在运输笼中。单笼猴被限制在单个运输笼中，而双笼猴则成对放在双倍大小的笼中。成对和成对的猴子在移出它们的笼子后都表现出明显的应激行为迹象。但是，与成对的动物相比，与成对的动物相比，应激相关的行为更为普遍，并且这些行为持续了较长的时间在模拟运输住房事件之后，比在一对猴子中住的要多。我们的数据证实食蟹猴的运输压力很大，并建议将食蟹猴成对成对地圈养和运输是有益的，从它们从源国繁殖场离开笼子直到它们到达最终使用国家/地区的实验室目的地。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号