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首页> 外文期刊>Spectrochimica acta, Part A. Molecular and biomolecular spectroscopy >Synthesis characterization and biological study of diorganotin(IV) complexes of monomethyl phthalate
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Synthesis characterization and biological study of diorganotin(IV) complexes of monomethyl phthalate

机译:邻苯二甲酸单甲酯二有机锡(IV)配合物的合成表征及生物学研究

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The synthesis and characterization of new coordination compounds of some organotin(IV) chlorides with monomethyl phthalate is reported; the ligand molecules appear to be bound to the tin atom through carbonyl oxygen atoms. Their structures have been characterized by elemental analyses, molar conductance, and bonding in these complexes is discussed in terms of their IR, H-1, C-13, Sn-119 NMR and Sn-119m Mossbauer spectral studies. The spectroscopic results obtained are in full agreement with the proposed 2:1 stoichiometry. The complexes soluble in DMSO have been screened against a wide spectrum of bacteria and the results obtained are quite promising. The LD50 values have also been determined in the albino rats. Some of the complexes also exhibit high anti-inflammatory activity. (c) 2005 Elsevier B.V. All rights reserved.
机译:报道了一些有机锡(IV)氯化物与邻苯二甲酸单甲酯的合成和表征。配体分子似乎通过羰基氧原子与锡原子结合。它们的结构已通过元素分析,摩尔电导和在这些配合物中的键合进行了表征,分别通过IR,H-1,C-13,Sn-119 NMR和Sn-119m Mossbauer光谱研究进行了讨论。获得的光谱结果与建议的2:1化学计量完全吻合。已针对多种细菌筛选了可溶于DMSO的复合物,获得的结果非常有希望。还已经在白化病大鼠中确定了LD50值。一些复合物还表现出高抗炎活性。 (c)2005 Elsevier B.V.保留所有权利。

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