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STATISTICAL METHODS IN PHYLOGENETIC AND EVOLUTIONARY INFERENCES

机译:系统发育和进化推论中的统计方法

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摘要

Molecular instruments are the most accurate methods in organisms'identification and characterization. Biologists are often involved in studies where the main goal is to identify relationships among individuals. In this framework, it is very important to know and apply the most robust approaches to infer correctly these relationships, allowing the right conclusions about phylogeny. In this review, we will introduce the reader to the most used statistical methods in phylogenetic analyses, the Maximum Likelihood and the Bayesian approaches, considering for simplicity only analyses regarding DNA sequences. Several studies will be showed as examples in order to demonstrate how the correct phylogenetic inference can lead the scientists to highlight very peculiar features in pathogens biology and evolution.
机译:分子仪器是生物鉴定和表征中最准确的方法。生物学家经常参与主要目的是识别个体之间关系的研究。在此框架中,了解并应用最可靠的方法来正确推断这些关系非常重要,从而可以得出有关系统发育的正确结论。在这篇综述中,我们将向读者介绍系统发育分析中最常用的统计方法,最大似然法和贝叶斯方法,为简化起见,仅考虑有关DNA序列的分析。为了说明正确的系统发育推断如何使科学家强调病原体生物学和进化中非常独特的特征,将进行一些研究作为示例。

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