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The use of indocyanine green fluorescence to assess anastomotic perfusion during robotic assisted laparoscopic rectal surgery

机译:吲哚菁绿荧光在机器人辅助腹腔镜直肠手术中评估吻合口灌注的作用

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Background: Decreased blood perfusion at an intestinal anastomosis may contribute to postoperative anastomotic leak (AL) resulting in substantial morbidity and mortality. Near-infrared (NIR) laparoscopy in conjunction with indocyanine green (ICG) allows for visualization of the microcirculation before formation of the anastomosis, thereby allowing the surgeon to choose the point of transection at an optimally perfused area. Methods: This is a retrospective case-control analysis examining the effectiveness of NIR + ICG in reducing the rate of AL after low anterior resection (LAR) for rectal cancer. Records of patients undergoing robot-assisted LAR for rectal cancer with and without ICG were analyzed for the years 2011 and 2012. Results: Among the 40 patients who underwent robotic LAR, NIR + ICG was used in 16 cases (41 %). Male patients accounted for the majority of cases in both groups (74 %). The median level of the anastomosis was 3.5 cm in the NIR + ICG group and 5.5 cm in the control group. There was no difference in the use of diverting ileostomy. In 3 patients (19 %), the use of NIR + ICG resulted in revision of the proximal bowel (colonic) transection point before formation of the anastomosis. The distal transection point was never revised. The rate of AL in the NIR + ICG group was 6 % versus 18 % in control group. Conclusions: ICG fluorescence may play a role in anastomotic tissue perfusion assessment and affect the AL rate. Larger prospective studies are needed to further validate this novel technology.
机译:背景:肠道吻合处的血液灌注减少可能会导致术后吻合口漏(AL),从而导致大量的发病率和死亡率。近红外(NIR)腹腔镜检查与吲哚菁绿(ICG)结合使用,可以在形成吻合之前可视化微循环,从而使外科医生可以选择最佳灌注区域的横切点。方法:这是一项回顾性病例对照分析,旨在检查NIR + ICG在降低直肠癌低位切除术(LAR)后降低AL发生率方面的有效性。分析了2011年和2012年接受机器人辅助LAR进行有或没有ICG的直肠癌患者的记录。结果:在接受机器人LAR的40例患者中,使用NIR + ICG的患者为16例(41%)。两组中男性患者占大多数(74%)。 NIR + ICG组的吻合术中位水平为3.5 cm,对照组为5.5 cm。回肠造口术的使用没有差异。在3例患者(19%)中,使用NIR + ICG导致吻合术形成之前近端肠(结肠)横切点的改变。远端横切点从未修改过。 NIR + ICG组的AL发生率为6%,而对照组为18%。结论:ICG荧光可能在吻合组织灌注评估中起作用,并影响AL率。需要进一步的前瞻性研究来进一步验证这项新技术。

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