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Linus Pauling's quest for the structure of proteins

机译：莱纳斯·鲍林（Linus Pauling）对蛋白质结构的追求

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摘要

Linus Pauling, arguably the greatest chemist of the twentieth century, never publicly admitted that there was a race for the determination of the structure of the most important biopolymers. But according to his competitors there was a race, in fact, there were two, and Pauling won one and lost the other. He had a tremendous amount of ideas, many of them worthless, but a few were spectacular. Not only did he make seminal discoveries, he was also a master of announcing them in a most dramatic way. Eventually, Pauling shifted toward politics and controversial issues, but his science ensured him his place among the greats. Here, we follow Pauling's route to the discovery of the alpha-helix; the defeat of the star-studded British team in the same quest; and a seemingly unrelated story about the fate of the theory of resonance that assured Pauling's victory yet at the same time it was excommunicated in the Soviet Union.
机译：可以说是二十世纪最伟大的化学家的莱纳斯·鲍林（Linus Pauling）从未公开承认要确定最重要的生物聚合物的结构存在一场竞赛。但根据他的竞争对手的说法，实际上有一场比赛，鲍林赢了一场，输了另一场。他有很多想法，其中许多毫无价值，但有一些很壮观。他不仅做出了开创性的发现，而且还是以最具戏剧性的方式宣布这些发现的大师。最终，鲍林转向政治和有争议的问题，但他的科学保证了他在大人物中的地位。在这里，我们遵循鲍林（Pau​​ling）的路线去发现α-螺旋。在同一任务中击败星光熠熠的英国队;还有一个关于共鸣理论命运的看似无关的故事，该故事确保了鲍林的胜利，但同时也被苏联驱逐出局。

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