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首页> 外文期刊>Surgical Endoscopy >Comparison of liver function after laparoscopically assisted and open distal gastrectomies for patients with liver disease.
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Comparison of liver function after laparoscopically assisted and open distal gastrectomies for patients with liver disease.

机译：肝病患者在腹腔镜辅助和开放远端胃切除术后肝功能的比较。

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BACKGROUND: Several studies have suggested that carbon dioxide (CO2) pneumoperitoneum may have an effect on liver function. This study aimed to compare liver function after laparoscopically assisted distal gastrectomy (LADG) and open distal gastrectomy (ODG) for patients with liver disease. METHODS: Between January 2006 and December 2007, the study enrolled 50 patients with EGC and liver disease including 18 liver cirrhosis patients, 3 fatty liver patients (n=3), and 29 healthy hepatitis B or C virus carriers. Albumin, total bilirubin, alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase levels as well as the volume of drainage in the LADG (n=18) and ODG (n=32) groups were determined to assess liver function. RESULTS: The albumin level on postoperative day 7 was significantly higher in the LADG group (3.5 mg/dl) than in the ODG group (3.1 mg/dl; p=0.042), and the volume of drainage on postoperative day 2 was significantly lower in the LADG group (154.3 ml) than in the ODG group (403.1 ml; p=0.013). Diuretics were needed by three patients (16.7%) in the LADG group and six patients (18.7%) in the ODG group for control of ascites (p=0.587). For the patients with liver cirrhosis, none of the parameters between the two groups were significantly different. CONCLUSION: For gastric cancer patients with chronic liver disease, LADG can be considered a safe surgical procedure showing surgical outcomes comparable with those for ODG.
机译：背景：多项研究表明，二氧化碳（CO2）气腹可能会影响肝功能。这项研究旨在比较肝病患者的腹腔镜辅助远端胃切除术（LADG）和开放远端胃切除术（ODG）后的肝功能。方法：2006年1月至2007年12月，该研究招募了50例患有EGC和肝病的患者，其中包括18例肝硬化患者，3例脂肪肝患者（n = 3）和29例健康的乙肝或丙肝病毒携带者。确定白蛋白，总胆红素，碱性磷酸酶，天冬氨酸转氨酶和丙氨酸转氨酶水平以及LADG（n = 18）和ODG（n = 32）组的引流量，以评估肝功能。结果：LADG组术后第7天的白蛋白水平（3.5 mg / dl）明显高于ODG组（3.1 mg / dl; p = 0.042），术后第2天的引流量明显降低LADG组（154.3 ml）比ODG组（403.1 ml; p = 0.013）。 LADG组中的三名患者（16.7％）和ODG组中的六名患者（18.7％）需要利尿剂来控制腹水（p = 0.587）。对于肝硬化患者，两组之间的参数均无显着差异。结论：对于患有慢性肝病的胃癌患者，LADG可被视为安全的手术方法，其手术结果与ODG相当。

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