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首页> 外文期刊>Surgical Endoscopy >A review of the composition, characteristics, and effectiveness of barrier mesh prostheses utilized for laparoscopic ventral hernia repair
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A review of the composition, characteristics, and effectiveness of barrier mesh prostheses utilized for laparoscopic ventral hernia repair

机译：腹腔镜腹疝修补术中使用的屏障网状假体的组成，特征和有效性的综述

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Background: The objective of this review was to provide an overview of the components that comprise each of the eight barrier mesh prostheses commonly utilized for LVHR and to review the current literature related to the characteristics and effectiveness of these materials to guide the general surgeon in selecting the most appropriate material for LVHR. Methods: Composite prostheses with permanent barriers (Bard? Composix? E/X, Bard? Composix? L/P, and DUALMESH ? Biomaterial) were compared to composite prostheses with absorbable barriers (C-QUR? Mesh, PROCEED? Surgical Mesh, Bard? Sepramesh? IP Composite, Parietex? Composite, and PHYSIOMESH?) using scanning electron microscopy and a review of the current preclinical and clinical literature. Results: Clinical studies and preclinical animal models have attempted to determine the adhesion characteristics and effectiveness of barrier mesh prostheses available for ventral hernia repair applications. However, it is difficult to make any definitive statements about the adhesion characteristics and effectiveness of these materials because all meshes were not included in all studies and likewise not compared under identical conditions. Overall, Parietex? Composite and DUALMESH ? Biomaterial were cited most frequently for improvement of adhesion characteristics, followed closely by Bard? Sepramesh? IP Composite and C-QUR? Mesh. Bard? Composix?, PROCEED? Surgical Mesh, and uncoated polypropylene were cited most frequently as having the most tenacious and extensive adhesions. Conclusions: Differences observed between the various barrier prostheses are likely attributable to the chemical composition of the barrier or the conditions required for resorption and metabolism of the barrier components. It is likely that the components of these barriers incite a wide range of inflammatory responses resulting in the range of adhesion coverage and tenacity observed in the preclinical and clinical studies reviewed. Clinical trials are needed to more appropriately define the clinical effectiveness of these barriers.
机译：背景：这项审查的目的是概述组成通常用于LVHR的八个屏障网状假体中的每一个的组件，并审查与这些材料的特性和有效性有关的当前文献，以指导普通外科医师选择最适合LVHR的材料。方法：将具有永久性障碍物的复合假体（Bard？Composix？E / X，Bard？Composix？L / P和DUALMESH？生物材料）与具有可吸收性障碍物的复合假体（C-QUR？网眼，PROCEED？手术网眼，Bard ？Sepramesh？IP复合材料，Parietex？复合材料和PHYSIOMESH？），使用扫描电子显微镜对当前的临床前和临床文献进行回顾。结果：临床研究和临床前动物模型已尝试确定可用于腹疝修补的屏障网状假体的粘附特性和有效性。但是，很难对这些材料的粘合特性和有效性做出任何明确的说明，因为所有研究均未包括所有网孔，并且同样未在相同条件下进行比较。总体而言，Parietex？复合和DUALMESH？人们最常引用生物材料来改善粘附特性，其次是Bard?。 Sepramesh？ IP复合和C-QUR？网格。诗人？ Composix ？，继续吗？外科网片和未涂覆的聚丙烯最常被认为具有最坚韧和最广泛的附着力。结论：各种屏障假体之间观察到的差异可能归因于屏障的化学组成或屏障成分吸收和代谢所需的条件。这些屏障的成分可能引起广泛的炎症反应，从而导致在所审查的临床前和临床研究中观察到一定范围的粘连覆盖率和韧性。需要进行临床试验以更恰当地定义这些障碍的临床有效性。

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