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首页> 外文期刊>Surgical Endoscopy >Endoscopic balloon dilatation for benign fibrotic strictures after curative nonsurgical treatment for esophageal cancer.
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Endoscopic balloon dilatation for benign fibrotic strictures after curative nonsurgical treatment for esophageal cancer.

机译：食管癌非手术治疗后的内镜球囊扩张术治疗良性纤维化狭窄。

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Endoscopic balloon dilatation (EBD) is performed to treat strictures after esophagectomy. However, little is known about using EBD for benign strictures that occur after nonsurgical treatments for esophageal cancer such as chemoradiotherapy (CRT) or endoscopic mucosal resection (EMR). The aim of this study was to evaluate the safety and efficacy of EBD for benign strictures after nonsurgical treatment compared with those after surgery.We identified 823 patients with esophageal cancer who completed definitive treatments between 2004 and 2007. Of these patients, 122 were enrolled in our study, including 60 who had surgery and 62 who did not have surgery (32 CRT, 30 EMR). The indication criteria for EBD were complaint of dysphagia and the inability to pass a conventional endoscope due to benign stricture. We retrospectively analyzed the safety and efficacy of EBD, and the measured outcomes were treatment success rate, time to treatment success, and refractory stricture rate.Perforation occurred in 3 (0.3 %) of 1,077 EBD sessions, with no bleeding. Efficacy was evaluated in 110 of the 122 patients. While the treatment success rate was over 90 % in both the surgery and the nonsurgery group, there was a significant difference in the median time to treatment success between both groups (2.3 vs. 5.6 months, p = 0.02: log-rank test). There was a significant difference in the median time to treatment success between CRT and surgery groups (7.0 months, p = 0.01), with no significant difference in the EMR group (4.4 months, p = 0.85). A significant difference in the refractory stricture rate was evident between the nonsurgery group (75 %) and the surgery group (45 %, p < 0.01).EBD for stricture after nonsurgical treatment of esophageal cancer was safe and effective. However, patients with benign strictures after nonsurgical treatment required significantly longer time to recover from dysphasia compared to those after surgery.
机译：内窥镜球囊扩张术（EBD）用于治疗食管切除术后的狭窄。但是，对于使用EBD进行食管癌非手术治疗（如放化疗，CRT或内窥镜黏膜切除术（EMR））后发生的良性狭窄，知之甚少。这项研究的目的是评估EBD与非手术后良性狭窄相比手术后的安全性和有效性。我们确定了823例食道癌患者，这些患者在2004年至2007年间完成了明确的治疗。在这些患者中，有122例入选了我们的研究包括60名接受手术的患者和62名未经手术的患者（32 CRT，30 EMR）。 EBD的指征标准为吞咽困难和由于良性狭窄而无法通过常规内窥镜。我们回顾性分析了EBD的安全性和有效性，测得的结局为治疗成功率，成功治疗时间和难治性狭窄率.1,077例EBD手术中有3例（0.3％）穿孔，无出血。在122例患者中有110例评估了疗效。尽管手术组和非手术组的治疗成功率均超过90％，但两组之间的成功治疗时间中位数存在显着差异（2.3个月与5.6个月，p = 0.02：对数秩检验）。 CRT组和手术组之间的成功治疗时间中位数存在显着差异（7.0个月，P = 0.01），而EMR组则没有显着差异（4.4个月，P = 0.85）。非手术组（75％）和手术组（45％，p <0.01）之间的难治性狭窄率有明显差异。食管癌非手术治疗后的EBD狭窄是安全有效的。但是，与手术后相比，非手术治疗后良性狭窄的患者需要更长的时间才能从吞咽困难中恢复。

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