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首页> 外文期刊>Surgical Endoscopy >Reduction in obesity-related comorbidities: Is gastric bypass better than sleeve gastrectomy?
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Reduction in obesity-related comorbidities: Is gastric bypass better than sleeve gastrectomy?

机译：减少与肥胖相关的合并症：胃旁路手术优于袖胃切除术吗？

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Background: Bariatric surgery is currently the most effective treatment for morbid obesity. It provides not only substantial weight loss, but also resolution of obesity-related comorbidities. Laparoscopic sleeve gastrectomy (LSG) has rapidly been gaining in popularity. However, there are limited data on the reduction of obesity-related comorbidities for LSG compared to laparoscopic Roux-en-Y gastric bypass (LRYGB). The aim of this study was to assess the effectiveness of laparoscopic LSG versus LRYGB for the treatment of obesity-related comorbidities. Methods: A total of 558 patients who underwent either LSG or LRYGB for morbid obesity at the Westchester Medical Center between April 2008 and September 2010 were included. Data were collected prospectively into a computerized database and reviewed for this study. Fisher's exact test analyses compared 30-day, 6-month, and 1-year outcomes of obesity-related comorbidities. Results: A total of 558 patients were included in the analysis of obesity-related comorbidity resolution; 200 underwent LSG and 358 underwent LRYGB. After 1 year, 86.2 % of the LSG patients had one or more comorbidities in remission compared to 83.1 % LRYGB patients (P = 0.688). With the exception of GERD (-0.09 vs. 50 %; P < 0.001), similar comorbidity remission rates were observed between LSG and LRYGB for sleep apnea (91.2 vs. 82.8 %; P = 0.338), hyperlipidemia (63 vs. 55.8 %; P = 0.633), hypertension (38.8 vs. 52.9 %; P = 0.062), diabetes (58.6 vs. 65.5 %; P = 0.638), and musculoskeletal disease (66.7 vs. 79.4 %; P = 0.472). Conclusions: Laparoscopic sleeve gastrectomy markedly improves most obesity-related comorbidities. Compared to LRYGB, LSG may have equal in reducing sleep apnea, hyperlipidemia, hypertension, diabetes, and musculoskeletal disease. LRYGB appears to be more effective at GERD resolution than LSG.
机译：背景：减肥手术是目前最有效的病态肥胖治疗方法。它不仅可以减轻体重，而且可以解决肥胖相关的合并症。腹腔镜袖胃切除术（LSG）已迅速普及。然而，与腹腔镜Roux-en-Y胃旁路术（LRYGB）相比，有关LSG肥胖相关合并症减少的数据有限。这项研究的目的是评估腹腔镜LSG与LRYGB在治疗肥胖相关合并症中的有效性。方法：纳入2008年4月至2010年9月在Westchester Medical Center接受LSG或LRYGB病态肥胖治疗的558例患者。将数据前瞻性收集到计算机数据库中，并进行本研究的回顾。 Fisher的精确测试分析比较了与肥胖相关的合并症的30天，6个月和1年结果。结果：共有558例患者被纳入了肥胖相关合并症的分析。 200名参加了LSG，358名参加了LRYGB。一年后，86.2％的LSG患者有一种或多种合并症缓解，而LRYGB患者为83.1％（P = 0.688）。除GERD（-0.09 vs. 50％; P <0.001）外，LSG和LRYGB的睡眠呼吸暂停合并症缓解率相似（91.2 vs. 82.8％; P = 0.338），高脂血症（63 vs. 55.8％） ; P = 0.633），高血压（38.8 vs. 52.9％; P = 0.062），糖尿病（58.6 vs. 65.5％; P = 0.638）和肌肉骨骼疾病（66.7 vs. 79.4％; P = 0.472）。结论：腹腔镜袖胃切除术可显着改善大多数肥胖相关合并症。与LRYGB相比，LSG在减少睡眠呼吸暂停，高脂血症，高血压，糖尿病和肌肉骨骼疾病方面可能具有同等效果。 LRYGB在GERD分辨率上似乎比LSG更有效。

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