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首页> 外文期刊>Surgical Endoscopy >Quality of life for patients with gastroesophageal reflux disease 2 years after laparoscopic fundoplication. Evaluation of the results obtained during the initial experience.
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Quality of life for patients with gastroesophageal reflux disease 2 years after laparoscopic fundoplication. Evaluation of the results obtained during the initial experience.

机译：腹腔镜胃底折叠术2年后患有胃食管反流疾病的患者的生活质量。评估在初始体验中获得的结果。

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摘要

BACKGROUND: Health-related quality of life (HRQL) is significantly affected by gastroesophageal reflux disease (GERD), and its evaluation is emerging as a factor important to select treatment options for GERD. Antireflux laparoscopic surgery improves HRQL. The aim of this study was to compare the preoperative and medium-term postoperative HRQL in patients submitted to laparoscopic fundoplication during the initial experience to verify its possible influence on HRQL outcomes. METHODS: Clinical assessment, endoscopy, and a previously validated HRQL index were performed before and 2 years after surgery in 32 patients who underwent at the beginning of our experience. RESULTS: The esophageal mucosa returned to normal 2 years after laparoscopic fundoplication in 81% of the patients. Heartburn was absent or occasional in 93%, and 65% were free of antisecretory drugs. All postoperative HRQL items were significantly improved (p <0.0001), with the postoperative curve of HRQL scores superposable to those of healthy Italian subjects (Italian normative sample). CONCLUSIONS: The initial phase of learning does not affect the improvement of HRQL observed after laparoscopic antireflux surgery, which is consistent with durable relief of symptoms and endoscopic healing. Evaluation of HRQL should be added to, and probably could replace in most cases, the objective postoperative testing.
机译：背景：与健康相关的生活质量（HRQL）受到胃食管反流疾病（GERD）的显着影响，其评估正在成为选择GERD治疗选择的重要因素。抗反流腹腔镜手术可改善HRQL。这项研究的目的是比较在初次经历腹腔镜胃底折叠术的患者的术前和中期HRQL，以验证其对HRQL结果的可能影响。方法：我们对32例在我们开始经验的患者进行了手术前和术后2年进行了临床评估，内窥镜检查和预先验证的HRQL指数。结果：81％的患者在腹腔镜胃底折叠术后2年，食管粘膜恢复正常。 93％的人没有胃灼热或偶有胃灼热，而65％的人没有抗分泌药。术后所有HRQL项目均得到显着改善（p <0.0001），且HRQL得分的术后曲线可与健康的意大利受试者（意大利标准样本）的曲线重叠。结论：学习的初始阶段不影响腹腔镜反流手术后观察到的HRQL的改善，这与症状的持久缓解和内窥镜愈合相一致。 HRQL的评估应添加到客观的术后检查中，并且在大多数情况下可能会代替。

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