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Laparoscopic adrenalectomy for pheochromocytoma. A comparison to aldosteronoma and incidentaloma.

机译:腹腔镜肾上腺切除术用于嗜铬细胞瘤。与醛固酮瘤和偶发瘤的比较。

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BACKGROUND: Laparoscopic adrenalectomy is a safe and effective treatment for most surgical diseases of the adrenal gland. However it has been suggested that catecholamine effects associated with pheochromocytoma render the laparoscopic approach a more challenging and a more morbid procedure. The purpose of this study was to compare the operative characteristics and outcomes of laparoscopic adrenalectomy for pheochromocytoma to those of aldosteronoma and incidentaloma. METHOD: Patient records and operative reports were retrospectively reviewed for demographics, diagnoses, operative management, and outcomes for patients undergoing laparoscopic adrenalectomy between June 1994 and July 2002 at two academic medical centers. A total of 74 patients were included and analyzed by diagnosis. Differences were considered statistically significant at p < 0.05. RESULTS: Twenty-eight patients with pheochromocytoma, 27 with aldosteronoma, and 19 with incidentally discovered nonfunctioning adrenal masses underwent laparascopic adrenalectomy. Patients undergoing resection for pheochromocytoma trended toward more operative blood loss (150 ml) compared to aldosteronoma (88 ml) and incidentaloma (75 ml). Eight patients were converted to an open procedure for a 10.8% conversion rate. The mean operative time was 171 min and there was a 10.8% perioperative complication rate. The mean hospital stay was 3.4 days. These results were not statistically significant between diagnostic groups. CONCLUSION: Despite concern about increased operative times and morbidity associated with pheochromocytoma, our experience supports that laparoscopic adrenalectomy may be performed as safely as, and achieve outcomes similar to, those for other diseases.
机译:背景:腹腔镜肾上腺切除术是对大多数肾上腺外科疾病的一种安全有效的治疗方法。然而,已经提出,与嗜铬细胞瘤相关的儿茶酚胺作用使腹腔镜方法更具挑战性和病态。这项研究的目的是比较腹腔镜肾上腺切除术治疗嗜铬细胞瘤与醛固酮瘤和偶发瘤的手术特点和结果。方法:回顾性地回顾了1994年6月至2002年7月间在两个学术医学中心接受腹腔镜肾上腺切除术的患者的病历和手术报告,以了解其人口统计学,诊断,手术管理和结局。纳入74例患者,并通过诊断进行分析。差异被认为具有统计学意义,p <0.05。结果:28例嗜铬细胞瘤,27例醛固酮瘤和19例偶然发现肾上腺功能不全的患者接受了腹腔镜肾上腺切除术。与醛固酮瘤(88 ml)和偶发瘤(75 ml)相比,接受嗜铬细胞瘤切除术的患者有更多的手术失血(150 ml)。八名患者被转换为开放式手术,转换率为10.8%。平均手术时间为171分钟,围手术期并发症发生率为10.8%。平均住院时间为3.4天。这些结果在诊断组之间没有统计学意义。结论:尽管担心与嗜铬细胞瘤相关的手术时间增加和发病率增加,但我们的经验支持腹腔镜肾上腺切除术可以像其他疾病一样安全地进行,并达到与其他疾病相似的结果。

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