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首页> 外文期刊>Surgical Endoscopy >Laparoscopy-assisted distal gastrectomy with D2 lymph node dissection for gastric cancer: technical and oncologic aspects.
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Laparoscopy-assisted distal gastrectomy with D2 lymph node dissection for gastric cancer: technical and oncologic aspects.

机译:腹腔镜辅助远端胃切除术与D2淋巴结清扫术治疗胃癌:技术和肿瘤方面。

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BACKGROUND: Laparoscopy-assisted distal gastrectomy (LADG) with lymph node dissection for advanced gastric cancer is still controversial. To evaluate the technical and oncologic feasibility and advantage of LADG with D2 lymph node dissection, the authors compared the surgical outcomes of LADG with D2 dissection and those of conventional open distal gastrectomy (ODG) for patients with early gastric cancer (EGC). METHODS: Between September 2004 and August 2005, the study enrolled 75 patients with a preoperative diagnosis of EGC. Of these 75 patients, 44 underwent LADG, and remaining 31 underwent ODG. All the patients received D2 lymph node dissection. Their clinicopathologic characteristics, postoperative outcomes, and retrieved lymph nodes were compared at each station. RESULTS: Although the operative time was significantly longer for the LADG group than for the ODG group, the perioperative recovery was shorter and, consequently, the postoperative hospital stay was significantly shorter for the LADG group (7.7 vs 9.4 days, respectively; p = 0.003). No significant differences were found in the total number of retrieved lymph nodes (37.2 vs 42.4; p > 0.05) or node stations (p > 0.05) between the two groups. CONCLUSIONS: LADG with D2 lymph node dissection is a safe and feasible procedure, and it is oncologically compatible with open gastrectomy. A large-scaled prospective randomized trial with advanced gastric cancer patients should be conducted to confirm the benefit of LADG.
机译:背景:腹腔镜辅助远端胃切除术(LADG)伴淋巴结清扫术治疗晚期胃癌仍存在争议。为了评估LADG D2淋巴结清扫术在技术和肿瘤学上的可行性和优势,作者比较了LADG D2清扫术和常规开放式远端胃切除术(ODG)对早期胃癌(EGC)患者的手术效果。方法:2004年9月至2005年8月,该研究招募了75例术前诊断为EGC的患者。在这75位患者中,有44位接受了LADG,其余31位接受了ODG。所有患者均行D2淋巴结清扫术。在每个站点比较他们的临床病理特征,术后结果和回收的淋巴结。结果:尽管LADG组的手术时间明显长于ODG组,但围手术期恢复时间较短,因此LADG组的术后住院时间明显缩短(分别为7.7天和9.4天; p = 0.003 )。两组之间的淋巴结总数(37.2 vs 42.4; p> 0.05)或淋巴结数目(p> 0.05)没有显着差异。结论:LADG D2淋巴结清扫术是一种安全可行的方法,在肿瘤学上与开放性胃切除术兼容。应当对晚期胃癌患者进行大规模的前瞻性随机试验,以确认LADG的益处。

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