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首页> 外文期刊>Surgical Endoscopy >Standard 'inject and cut' endoscopic mucosal resection technique is practical and effective in the management of superficial colorectal neoplasms.
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Standard 'inject and cut' endoscopic mucosal resection technique is practical and effective in the management of superficial colorectal neoplasms.

机译:标准的“注射和切割”内窥镜黏膜切除术在浅表性结直肠肿瘤的治疗中是实用且有效的。

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BACKGROUND: Standard polypectomy techniques may be contributing to ineffective eradication of colonic superficial neoplasia, an increasing number of which are nonpolypoid. We aimed to demonstrate the practicality and efficacy of the "inject and cut" endoscopic mucosal resection (EMR) technique in routine clinical practice. METHODS: Colonic EMRs performed for polypoid and nonpolypoid lesions at a tertiary institution were prospectively collected and analyzed for efficacy, and short and long-term complications. RESULTS: 224 colonic neoplasms (143 flat, 65 sessile and 16 subpedunculated) were excised by the standard inject-and-cut method, with standard accessories. The median size of all lesions was 10 mm (range 2-50 mm) and 110 (49.2%) lesions were located in the proximal colon. Histological completeness of resection was achieved in 87% of cases. Of the lesions 77.2% were dysplastic, with 5 cases of carcinoma in situ and 18 severely dysplastic adenomas. Complications included bleeding in five cases (2.2 %) and a single case of perforation (0.4%). All complications were managed endoscopically. Median follow up at 24 +/- 16 months (range 12-84 months) revealed a 7.2% local recurrence rate, all of which were subsequently eradicated by repeat EMR. CONCLUSIONS: Standard inject-and-cut colonic EMR is practical and effective in the eradication of superficial colonic neoplasia.
机译:背景:标准的息肉切除术技术可能会导致根除结肠浅表性赘生物的效果不佳,其中越来越多的是非息肉样息肉。我们旨在证明在常规临床实践中“注射和切割”内窥镜黏膜切除术(EMR)技术的实用性和有效性。方法:前瞻性收集在大专院校针对息肉样和非息肉样病变进行的结肠EMR,并分析其疗效以及短期和长期并发症。结果:采用标准的注射切割法和标准附件,切除了224例结肠肿瘤(143例扁平,65例无蒂和16例有蒂)。所有病变的中位大小为10毫米(范围2-50毫米),其中110个病变(49.2%)位于近端结肠。 87%的病例达到了切除的组织学完整性。病变中有77.2%为增生异常,其中5例为原位癌,18例为严重增生性腺瘤。并发症包括五例出血(2.2%)和一例穿孔(0.4%)。内镜处理所有并发症。在24 +/- 16个月(12-84个月)中位随访结果显示局部复发率为7.2%,所有这些随后均通过重复EMR消除。结论:标准的切开式结肠EMR在根除浅表性结肠肿瘤中是实用和有效的。

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