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Pancreatic Neuroendocrine Neoplasms

机译:胰腺神经内分泌肿瘤

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Pancreatic neuroendocrine neoplasms (Pan-NENs) are rare but clinically important lesions. Pan-NENs are known for and often categorized by their capacity to produce clinical syndromes mediated by the production of hormones. Despite sometimes presenting dramatically from excessive hormone production, not all Pan-NENs produce functional hormone, and they can pose diagnostic challenges to practicing pathologists. Distinguishing Pan-NENs from mimics can be crucial, because Pan-NENs carry different prognoses and have unique treatments available due to their specific biological properties. This article reviews the current categorization and features of Pan-NENs.
机译:胰腺神经内分泌肿瘤(Pan-NENs)很少见,但在临床上很重要。 Pan-NENs以产生激素介导的临床综合症的能力而闻名,并经常按其分类。尽管有时会因过量的激素产生而显着地表现出来,但并非所有的Pan-NEN都能产生功能性激素,而且它们可能会对执业病理学家提出诊断挑战。区分泛神经元与模拟物可能至关重要,因为泛神经元具有不同的预后,并且由于其特定的生物学特性而具有独特的治疗方法。本文介绍了Pan-NEN的当前分类和功能。

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