Cutaneous CD30-positive lymphoproliferative disorders

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Cutaneous CD30-positive lymphoproliferative disorders

机译：皮肤CD30阳性淋巴组织增生性疾病

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Cutaneous CD30+ lymphoproliferative disorders are the second most common types of cutaneous T-cell lymphomas. They represent a well-defined spectrum encompassing lymphomatoid papulosis (LyP), primary cutaneous anaplastic large-cell lymphoma (pcALCL), and borderline lesions. They share the expression of CD30 as a common phenotypic hallmark, but they differ in their clinical presentation, course, and histologic features. New variants have been recently identified, including CD8+ epidermotropic LyP type D, angioinvasive LyP type E, and ALK-positive pcALCL. This review describes clinical, histopathologic, and phenotypic variants; their differential diagnoses (benign and malignant); and the role of CD30 as a diagnostic, prognostic, and therapeutic marker.

机译：皮肤CD30 +淋巴增生性疾病是第二大最常见的皮肤T细胞淋巴瘤。它们代表了明确的频谱，包括淋巴瘤样丘疹病（LyP），原发性皮肤间变性大细胞淋巴瘤（pcALCL）和边缘性病变。它们具有共同表达CD30的表型特征，但在临床表现，病程和组织学特征上却有所不同。最近发现了新的变体，包括CD8 +表皮性LyP型D，血管浸润型LyP E和ALK阳性pcALCL。这篇综述描述了临床，组织病理学和表型变异;他们的鉴别诊断（良性和恶性）;以及CD30作为诊断，预后和治疗标志物的作用。

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《Surgical pathology clinics》 |2014年第2期|共26页
作者
KempfW.;
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正文语种 eng
中图分类病理学;
关键词
Anaplastic large-cell lymphoma; Borderline; CD30; Clinico-pathological correlation; Cutaneous; Lymphoma; Lymphomatoid papulosis; Systemic;

机译：间变性大细胞淋巴瘤;边界线;CD30;临床病理相关性;瞬时性;淋巴瘤;淋巴瘤样丘疹;全身性;

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1. Mucosal CD30-positive T-cell lymphoproliferations of the head and neck show a clinicopathologic spectrum similar to cutaneous CD30-positive T-cell lymphoproliferative disorders [J] . Andrew P Sciallis, Mark E Law, David J Inwards, Modern Pathology . 2012,第7期

机译：头部和颈部的粘膜CD30阳性T细胞淋巴组织增生显示类似于皮肤CD30阳性T细胞淋巴组织增生性疾病的临床病理学频谱
2. Methotrexate-associated primary cutaneous CD30-positive cutaneous T-cell lymphoproliferative disorder [J] . Wederson M Claudino, Bradley Gibson, William Tse, American Journal of Blood Research . 2016,第1期

机译：甲氨蝶呤相关原发性皮肤CD30阳性皮肤T细胞淋巴增生性疾病
3. EORTC, ISCL, and USCLC consensus recommendations for the treatment of primary cutaneous CD30-positive lymphoproliferative disorders: lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma. [J] . Kempf W, Pfaltz K, Vermeer MH, Blood: The Journal of the American Society of Hematology . 2011,第15期

机译：EORTC，ISCL和USCLC对于治疗原发性皮肤CD30阳性的淋巴增生性疾病的共识性建议：淋巴瘤样丘疹和原发性皮肤间变性大细胞淋巴瘤。
4. An integrated system for the monitoring of therapy and drug's side effects in Lymphoproliferative disorders [C] . Luca Vollero, Ombretta Annibali, Emiliano Schena, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2017

机译：治疗治疗和药物副作用的综合系统淋巴抑制性疾病
5. Treatment and modeling of Epstein-Barr virus post-transplant lymphoproliferative disorder [D] . Jian, Tan Wei. 2016

机译：移栽后淋巴抑制性疾病综合症治疗与建模
6. Methotrexate-associated primary cutaneous CD30-positive cutaneous T-cell lymphoproliferative disorder: a case illustration and a brief review [O] . Wederson M Claudino, Bradley Gibson, William Tse, 2016

机译：甲氨蝶呤相关的原发性皮肤CD30阳性的皮肤T细胞淋巴组织增生性疾病：一例病例和简要回顾
7. Mucosal CD30-positive T-cell lymphoproliferations of the head and neck show a clinicopathologic spectrum similar to cutaneous CD30-positive T-cell lymphoproliferative disorders [O] . Andrew P Sciallis, Mark E Law, David J Inwards, 2012

机译：头部和颈部的粘膜CD30阳性T细胞淋巴抑制液显示出类似于皮肤CD30阳性T细胞淋巴抑制性疾病的临床病理光谱

Cutaneous CD30-positive lymphoproliferative disorders

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