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首页> 外文期刊>Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer >The effects of exercise therapy on delirium in cancer patients: a retrospective study.
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The effects of exercise therapy on delirium in cancer patients: a retrospective study.

机译:运动疗法对癌症患者del妄的影响:一项回顾性研究。

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PURPOSE: The present study aimed to investigate the effects of exercise therapy on delirium in cancer patients. METHODS: We conducted a retrospective study of cancer patients who were admitted to Kyoto University Hospital and referred to the Palliative Care Team. Subjects were divided into two groups [an exercise therapy group (EG) and a non-exercise therapy group (NG)] according to whether exercise therapy was being used for early ambulation at the time delirium occurred. To examine whether any characteristics differed significantly between the two groups, we also compared age, performance status, alcohol use, existence of metastatic brain tumors or preexisting CNS illnesses, levels of opioid exposure, and survival time from the onset of delirium. Moreover, we investigated whether there were differences in antipsychotic drug doses administered between these two groups in order to better analyze the specific effects of exercise therapy on the course of delirium. RESULTS: EG and NG groups did not differ significantly in terms of any characteristics. The administered dose of antipsychotic drugs was significantly lower in the EG group versus the NG group (2.198 mg versus 5.533 mg, p = 0.036). In comparison, the dose of opioids used did not differ significantly between the two study groups. CONCLUSIONS: Given the relatively low antipsychotic doses used, it is conceivable that delirium symptoms were attenuated in patients who received exercise therapy. This study suggests that exercise therapy may be useful as one environmental/supportive intervention for delirium.
机译:目的:本研究旨在研究运动疗法对癌症患者del妄的影响。方法:我们对京都大学附属医院的癌症患者进行了回顾性研究,并转诊至姑息治疗团队。根据del妄发生时是否将运动疗法用于早期步行,将受试者分为两组[运动疗法组(EG)和非运动疗法组(NG)]。为了检查两组之间的特征是否存在显着差异,我们还比较了年龄,机能状况,饮酒,转移性脑肿瘤或先前存在的中枢神经系统疾病的存在,阿片类药物的暴露水平以及from妄发作后的生存时间。此外,我们调查了两组之间服用抗精神病药物的剂量是否存在差异,以便更好地分析运动疗法对ir妄过程的特定影响。结果:EG和NG组在任何特征方面均无显着差异。与NG组相比,EG组抗精神病药的给药剂量显着降低(2.198 mg对5.533 mg,p = 0.036)。相比之下,两个研究组之间使用的阿片类药物剂量没有显着差异。结论:鉴于使用的抗精神病药剂量相对较低,可以想象接受运动疗法的患者的del妄症状有所减轻。这项研究表明,运动疗法可用作one妄的一种环境/支持性干预措施。

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