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首页> 外文期刊>PACE: Pacing and clinical electrophysiology >Initial clinical experience with a dual chamber rate responsive implantable cardioverter defibrillator.
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Initial clinical experience with a dual chamber rate responsive implantable cardioverter defibrillator.

机译：使用双腔室频率响应的植入式心脏复律除颤器的初步临床经验。

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The present study reports the first clinical experience with the Photon DR dual chamber rate responsive ICD. Fifty-seven patients (mean age 67.6 +/- 10 years) with a mean LVEF of 0.332 in NYHA Class I (30%), II (51%), or III (19%) met the implant criteria. Tachyarrhythmia diagnoses included VF (21%), VT (49%), or VT/VF (30%). Additional bradycardia pacing diagnoses included AV block (18%), sinus node dysfunction (5%), and sinus bradycardia (11%). All patients were followed on a long-term basis. A device-based direct current fibrillator (DC fibber) successfully induced VF in 96.2% of 243 attempted inductions. Detection times (2.86 +/- 0.47 s) and redetection times (1.29 +/- 0.32 s) compared favorably with historic controls using a morphology detection (MD) clinical data. Defibrillation energy and voltage thresholds were 10.4 +/- 5.5 J (range 3-28) and 421 V +/- 108 (range 230-696), respectively. Ninety-two clinical arrhythmias were recorded. Using a nominal nonindividualized algorithm, the sensitivity for VT detection was 100% and specificity for SVT rejection 81%. There were six patient deaths (2 nonsudden arrhythmic, 2 cardiac, 2 other). In conclusion, early clinical experience with the Photon DR ICD supports its safety, efficacy, and ability to provide advanced dual chamber ICD features.
机译：本研究报告了Photon DR双腔室速率反应性ICD的首次临床经验。 NYHA I级（30％），II级（51％）或III级（19％）的平均LVEF为0.332的57例患者（平均年龄67.6 +/- 10岁）符合植入标准。快速性心律失常的诊断包括VF（21％），VT（49％）或VT / VF（30％）。其他心动过缓的诊断包括房室传导阻滞（18％），窦房结功能障碍（5％）和窦性心动过缓（11％）。长期随访所有患者。基于设备的直流原纤化器（DC纤维）在243次尝试的96.2％的尝试中成功诱导了VF。使用形态学检测（MD）临床数据与历史对照相比，检测时间（2.86 +/- 0.47 s）和重检测时间（1.29 +/- 0.32 s）优越。除颤能量和电压阈值分别为10.4 +/- 5.5 J（范围3-28）和421 V +/- 108（范围230-696）。记录了92例临床心律失常。使用名义上的非个性化算法，VT检测的灵敏度为100％，SVT排斥的特异性为81％。有6例患者死亡（2例非突发性心律不齐，2例心脏性，2例其他）。总之，光子DR ICD的早期临床经验支持其安全性，功效和提供高级双腔ICD功能的能力。

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