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首页> 外文期刊>PACE: Pacing and clinical electrophysiology >Correlation between defibrillation shock outcome and coherence in electrocardiograms.
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Correlation between defibrillation shock outcome and coherence in electrocardiograms.

机译:除颤电击结果与心电图相关性之间的相关性。

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Cycle periods in ECG during VF are correlated with periods of reentrant activation. The ECGs recorded from different locations on the thorax were contributed to from electrical activations within the heart in approximately inverse proportion of their distance from the recording sites. Similarity in cycle periods between ECGs recorded from two locations, therefore, can be used as an index of spatiotemporal similarity in the rate of activation. In the present study coherence was used, which is a mathematical function that measures the degree of similarity that two signals exhibit at specific cycle periods, to test if spatiotemporal similarity in cycle periods between pairs of orthogonal ECGs was correlated with defibrillation shock outcome. The authors estimated time-varying coherence from orthogonal ECGs during 10 seconds of electrically induced VF, which was terminated with a defibrillation shock with a 50% probability of successful outcome. Defibrillation shocks were delivered between a coil electrode placed at the right ventricular apex and a subdermal patch electrode. Time-varying coherencies between pairs of ECGs were estimated using an adaptive least mean square algorithm. Time-coherence surfaces were integrated within a frequency region centered at the dominant frequency. Data were collected from ten dogs during 206 (48%) successful and 221 (52%) unsuccessful trials. The results showed that coherencies between the sagittal-transverse pair were 10%-15% higher (P < 0.05) for successful than unsuccessful trials. The correlation between coherence and defibrillation outcome suggests that more defibrillation shocks occurred when the degree of spatial similarity in the rate of activations was higher terminated VF, than those that occurred at other times. These results are consistent with a hypothesis, recently proposed by others, that more uniform activation within regions of the heart that receive low potential gradients during shock may increase the probability of successful defibrillation.
机译:VF期间ECG的循环周期与折返激活周期相关。从胸腔不同位置记录的心电图是由心脏内的电激活导致的,其电离其与记录部位的距离大致成反比。因此,从两个位置记录的ECG之间的循环周期相似性可以用作激活率时空相似性的指标。在本研究中,使用了相干性,该相干性是一种数学函数,用于测量两个信号在特定周期内表现出的相似程度,以测试正交ECG对之间的周期内时空相似性是否与除颤电击结果相关。作者估计了在10秒钟电诱发的VF期间,来自正交ECG的时变相干性,该相干性以除颤电击终止,成功率为50%。除颤电击在位于右心室顶点的线圈电极和皮下贴片电极之间传递。使用自适应最小均方算法估算心电图对之间的时变相干性。时间相干表面集成在以主频率为中心的频率区域内。在206次(48%)成功和221次(52%)不成功的试验中,从十只狗中收集了数据。结果表明,成功的试验比不成功的试验的矢状横断面对之间的相干性高10%-15%(P <0.05)。相干性和除颤结果之间的相关性表明,当激活速率的空间相似度高于终止VF时,发生的除颤电击次数要多于其他时间。这些结果与其他人最近提出的假设相一致,即在电击期间接收低电位梯度的心脏区域内更均匀的激活可能会增加除颤成功的可能性。

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