...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>PACE: Pacing and clinical electrophysiology >Ventricular endocardial right bifocal stimulation in the treatment of severe dilated cardiomyopathy heart failure with wide QRS.
【24h】

Ventricular endocardial right bifocal stimulation in the treatment of severe dilated cardiomyopathy heart failure with wide QRS.

机译：室性心内膜右双灶刺激治疗宽QRS波治疗严重扩张型心肌病心力衰竭。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The QRS widening by ventricular conventional pacing impairs the systolic and diastolic functions and increases mitral regurgitation. The aim of this study was to compare conventional pacing to an alternative stimulation mode with a narrower QRS using two leads in the RV. Thirty-nine (25 men, 14 women; mean age 60.1 +/- 15.1 years) dilated cardiomyopathy patients (Chagas' disease [n = 17], coronariopathy [n = 9], AV ablation for tachycardiomyopathy [n = 3], and other [n = 10]) with cardiac failure (NYHA 3.1 +/- 0.8), pacemaker indication, and chronic AV block (22 AF) had endocardial pacemaker implantations (27 Biotronik, 12 Guidant). Two RV leads (one septal, one conventional [RV apex] were connected, respectively, to the atrial and ventricular pacemaker plugs. After clinical stabilization they were studied under three stimulation modes in the same session: AAI (septal), VVI (conventional), and ventricular endocardial right bifocal stimulation (VERBS) (DDT/DVI/DDD = AV interval = 15/10 ms). In comparison to conventional pacing, VERBS increased ejection fraction (0.124), cardiac output (19.5%), and peak filling rate (31.0%), and decreased QRS duration (24.7%), left atrium area (11.9%), mitral regurgitation area (32.3%), the diastolic transmitral flow (E/A relation) (19.3%), and the propagation flow time (18.0%) from the mitral valve to the left ventricular apex (tE_col), (P < 0.05). The quality-of-life showed an impressive score reduction of 50.4%. The septal stimulation alone showed a less expressive benefit. In severe dilated cardiomyopathy with classic pacemaker indication, VERBS showed significantly better performance than the septal or the conventional stimulation alone. There was a good systolic and a remarkable diastolic improvement causing an important reduction in the quality-of-life score.
机译：心室常规起搏使QRS增宽损害了收缩和舒张功能，并增加了二尖瓣反流。这项研究的目的是将常规起搏与使用RV中的两个导线的QRS较窄的替代刺激模式进行比较。三十九名（25名男性，14名女性;平均年龄60.1 +/- 15.1岁）扩张型心肌病患者（查加斯病[n = 17]，冠状动脉病[n = 9]，房室速消融性心动过速[n = 3]和其他[n = 10]），伴有心力衰竭（NYHA 3.1 +/- 0.8），起搏器适应症和慢性房室传导阻滞（22 AF）的患者植入了心内膜起搏器（Biotronik，12 Guidant）。将两个RV导线（一个间隔，一个常规的[RV顶点]分别连接到心房和心室起搏器塞上。在临床稳定后，在同一阶段以三种刺激模式对它们进行了研究：AAI（间隔），VVI（常规） ，以及心室右心房双焦点刺激（VERBS）（DDT / DVI / DDD = AV间隔= 15/10 ms）与传统起搏相比，VERBS增加了射血分数（0.124），心输出量（19.5％）和峰值充盈率（31.0％），QRS持续时间减少（24.7％），左心房面积（11.9％），二尖瓣反流面积（32.3％），舒张末梢血流（E / A关系）（19.3％）和传播血流从二尖瓣到左心尖的时间（tE_col）（18.0％），（P <0.05）。生活质量显示得分显着降低50.4％。仅间隔刺激显示的疗效较差。具有经典起搏器适应症的严重扩张型心肌病，VERBS表现出明显更好的性能比隔片或常规刺激单独的发声。收缩期良好，舒张期显着改善，导致生活质量评分显着降低。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号