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首页> 外文期刊>PACE: Pacing and clinical electrophysiology >Systolic and diastolic function with alternate and combined site pacing in the right ventricle.
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Systolic and diastolic function with alternate and combined site pacing in the right ventricle.

机译：收缩和舒张功能，右心室交替和联合起搏。

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摘要

We hypothesized that pacing at two ventricular sites simultaneously would activate the myocardium more rapidly and improve ventricular function. We studied the effect of pacing at the right ventricular outflow tract (RVOT) and the RV apex (RVA) on systolic and diastolic function. In 14 patients with a reduced systolic ejection fraction < 40% (mean EF 32% +/- 4%) we measured RV pressures, left ventricular pressures, EF, cardiac output, peak dP/dt, peak negative dP/dt, and the time constant of relaxation, Tau, during intrinsic rhythm, atrial pacing and DVI pacing at the RVA, the RVOT, and both RV sites combined in random order. Repeated measures analysis of variance showed no significant differences in any of these parameters. The highest absolute values of dP/dt were observed during sinus rhythm and the lowest with RVA pacing. This parameter tended to improve progressively with pacing in the RVOT and at both sites. Peak negative dP/dt showed a similar nonsignificant trend. Conclusion: These data suggest that in patients with poor LV function, there may be subtle improvements in diastolic and systolic function with pacing in the RVOT and at combined sites in the RV compared to traditional RVA pacing.
机译：我们假设在两个心室部位同时起搏会更快地激活心肌并改善心室功能。我们研究了在右心室流出道（RVOT）和右心尖（RVA）起搏对收缩和舒张功能的影响。在14例收缩期射血分数低于40％（平均EF 32％+/- 4％）的患者中，我们测量了RV压力，左心室压力，EF，心输出量，峰值dP / dt，峰值负dP / dt和RVA，RVOT和两个RV部位固有的节律，心房起搏和DVI起搏期间的松弛时间常数Tau，以随机顺序组合。重复测量方差分析表明，这些参数中的任何一个均无显着差异。在窦性心律期间观察到最高的dP / dt绝对值，而在RVA起搏时观察到的绝对值最低。随着RVOT和两个位置的起搏，该参数趋于逐渐提高。峰值负dP / dt表现出相似的无显着趋势。结论：这些数据表明，与传统的RVA起搏相比，在RVOT中以及在RV的合并部位，LV功能差的患者的舒张和收缩功能可能会有细微的改善。

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