A SHORT SYNTHESIS OF 1-VINYLURACIL AND 1-VINYLTHYMINE

Zhou JL.; Shevlin PB.

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A SHORT SYNTHESIS OF 1-VINYLURACIL AND 1-VINYLTHYMINE

机译：短时间合成1-乙烯基尿素和1-乙烯基胸苷

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1-Vinyluracil and 1-vinylthymine, monomers for nucleic acid bases attached functional polymers, were synthesized for the first time from uracil and thymine in 3 steps in 54% and 50% overall yields using the Mitsunobu reactions of 2a and 2b with 2-chloroethanol as a key step. [References: 17]

机译：使用2a和2b与2-氯乙醇的Mitsunobu反应，从尿嘧啶和胸腺嘧啶分3步以54％和50％的总产率首次合成了连接核酸碱基的功能聚合物的1-乙烯基尿嘧啶和1-乙烯基胸腺嘧啶。作为关键步骤。 [参考：17]

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《Synthetic Communications》 |1997年第20期|共7页
作者
Zhou JL.; Shevlin PB.;
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正文语种 eng
中图分类有机化学;
关键词
Phase-transfer conditions; Alkylation; Monomers; Analogs; Thymine;

机译：相转移条件;烷基化;单体;类似物;胸腺嘧啶;

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专利

1. A SHORT SYNTHESIS OF 1-VINYLURACIL AND 1-VINYLTHYMINE [J] . Zhou JL., Shevlin PB. Synthetic Communications . 1997,第20期

机译：短时间合成1-乙烯基尿素和1-乙烯基胸苷
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A SHORT SYNTHESIS OF 1-VINYLURACIL AND 1-VINYLTHYMINE

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