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首页> 外文期刊>Sleep medicine >Advanced sleep-wake rhythm in adults born prematurely: Confirmation by actigraphy-based assessment in the Helsinki Study of Very Low Birth Weight Adults
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Advanced sleep-wake rhythm in adults born prematurely: Confirmation by actigraphy-based assessment in the Helsinki Study of Very Low Birth Weight Adults

机译：早产成年人的高级睡眠-觉醒节律：极低出生体重成年人的赫尔辛基研究中通过行为描记法评估得到证实

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摘要

Objective: Previous studies have suggested a propensity towards morningness in teenagers and adults born preterm. We set out to study sleep in a subsample from The Helsinki Study of Very Low Birth Weight Adults cohort, with emphasis on sleep timing, duration, and quality. We compared young adults who were born prematurely at very low birth weight (VLBW; <1500 g) with controls born at term. Methods: We measured sleep by actigraphy in young adults aged 21-29 years. A total of 75 individuals (40 VLBW and 35 controls) provided adequate data. Group differences in sleep parameters were analyzed using t-test and linear regression models. Results: VLBW adults woke up on average 40 min earlier [95% confidence interval (CI), 9-70] and reported 40 min earlier get up time (95% CI, 8-71) than did the controls. The difference remained after adjustment for confounders. We found no group difference in sleep duration or measures of sleep quality. Conclusion: Our findings of earlier rising in the VLBW group are suggestive of an advanced sleep phase in that group. These results reinforce previous suggestions that chronotype may be programmed early during life.
机译：目的：先前的研究表明早产的少年和成年人倾向于晨起。我们着手在《赫尔辛基非常低出生体重成年人研究》的子样本中研究睡眠，重点是睡眠时间，持续时间和质量。我们将出生时体重很低（VLBW; <1500 g）的早产儿与足月出生的对照组进行了比较。方法：我们通过书法记录了21-29岁年轻人的睡眠状况。共有75个人（40名VLBW和35名对照）提供了足够的数据。使用t检验和线性回归模型分析睡眠参数的组差异。结果：VLBW成人平均比起床时间早40分钟[95％置信区间（CI），9-70]，并且报告起床时间比起床时间早40分钟（95％CI，8-71）。调整混杂因素后，差异仍然存在。我们没有发现睡眠时间或睡眠质量的组差异。结论：我们在VLBW组中较早上升的发现提示该组处于晚期睡眠阶段。这些结果加强了以前的建议，即可以在生命早期对表型进行编程。

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