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首页> 外文期刊>Pancreatology: official journal of the International Association of Pancreatology (IAP) ... [et al.] >Update of the Atlanta Classification of severity of acute pancreatitis: should a moderate category be included?
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Update of the Atlanta Classification of severity of acute pancreatitis: should a moderate category be included?

机译:亚特兰大急性胰腺炎严重程度分类的更新:是否应包括中度类别?

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摘要

BACKGROUND: Persistent and multiple organ failure (POF and MOF) are predictive of death in acute pancreatitis (AP). Local complications without organ failure are associated with morbidity but a low risk of mortality. AIM: To design a three-category classification of AP severity and to compare it with the Atlanta Classification (AC) in terms of morbidity and mortality. METHOD: Severe AP was defined as death, POF (>48 h) or MOF. Moderate AP was defined as the presence of acute collections and/or pancreatic necrosis. Mild AP was defined by exclusion. We compared this classification with AC in 144 episodes of AP. RESULTS: In the three-category classification, severe AP was associated with significantly more frequent intensive care unit admission, invasive treatment and mortality than moderate and mild AP (p < 0.01). Severe AP patients required longer hospital stay and more nutritional support than mild AP patients (p < 0.01). Patients with moderate AP had significantly longer hospital stay and more need for nutritional support than patients with mild AP (p < 0.01). Five patients died, all of them with MOF and/or POF. CONCLUSIONS: A three-category classification distinguishes three homogeneous groups of severity.
机译:背景:持续性和多器官功能衰竭(POF和MOF)可预测急性胰腺炎(AP)的死亡。没有器官衰竭的局部并发症与发病率有关,但死亡风险低。目的:设计AP严重程度的三类分类,并将其与亚特兰大分类(AC)的发病率和死亡率进行比较。方法:严重AP定义为死亡,POF(> 48小时)或MOF。中度AP被定义为存在急性集合和/或胰腺坏死。轻度AP是通过排除定义的。我们在144例AP中将该分类与AC进行了比较。结果:在三类分类中,重度AP与中重度AP相比,重症监护病房入院,侵入性治疗和死亡率显着更高(p <0.01)。重度AP患者比轻度AP患者需要更长的住院时间和更多的营养支持(p <0.01)。与轻度AP患者相比,中度AP患者的住院时间明显更长,并且需要更多的营养支持(p <0.01)。五例患者死亡,所有患者均患有MOF和/或POF。结论:三类分类区分了严重程度的三个同类组。

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