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首页> 外文期刊>Pancreatology: official journal of the International Association of Pancreatology (IAP) ... [et al.] >Non-occlusive mesenteric ischemia and its associated intestinal gangrene in acute pancreatitis.
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Non-occlusive mesenteric ischemia and its associated intestinal gangrene in acute pancreatitis.

机译：急性胰腺炎的非阻塞性肠系膜缺血及其相关的肠坏疽。

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摘要

BACKGROUND/AIMS: Non-occlusive mesenteric ischemia (NOMI) has been defined as diffuse intestinal ischemia that often results in intestinal gangrene in the presence of a patent arterial trunk. The prevalence and nature of NOMI in acute pancreatitis was investigated. METHODS: A total of 120 consecutive patients with acute pancreatitis managed in the Department of Surgery II, Kumamoto University Medical School, from April 1992 through December 2002, were investigated retrospectively. Among them, 60 patients had the severe form. RESULTS: The overall mortality of acute pancreatitis patients was 8.3% (10/120). The prevalence and mortality of acute pancreatitis associated with NOMI were 6.7% (8/120) and 63% (5/8), respectively, while those of patients with NOMI-associated intestinal gangrene were 4.2% (5/120) and 100% (5/5), respectively. The mortality of patients with severe acute pancreatitis who did not develop NOMI was 10% (5/52). All patients with NOMI-associated intestinal gangrene quickly progressed and subsequently died of multiple organ failure. Plasma creatine phosphokinase (CPK) and lactate levels were elevated significantly in patients with NOMI. CONCLUSION: Acute pancreatitis associated with NOMI was extremely severe. If the plasma CPK and lactate levels are extremely high, NOMI should be suspected.
机译：背景/目的：非闭塞性肠系膜缺血（NOMI）已被定义为弥漫性肠缺血，在存在动脉干的情况下常导致肠坏疽。研究了急性胰腺炎中NOMI的患病率和性质。方法：回顾性研究了1992年4月至2002年12月在熊本大学医学院第二外科治疗的120例急性胰腺炎患者。其中，60例为重症。结果：急性胰腺炎患者的总死亡率为8.3％（10/120）。与NOMI相关的急性胰腺炎的患病率和死亡率分别为6.7％（8/120）和63％（5/8），而与NOMI相关的肠坏疽患者的患病率和死亡率分别为4.2％（5/120）和100％ （5/5）。未发展为NOMI的重症急性胰腺炎患者的死亡率为10％（5/52）。所有与NOMI相关的肠坏疽患者均迅速进展，随后死于多器官功能衰竭。 NOMI患者的血浆肌酸磷酸激酶（CPK）和乳酸水平显着升高。结论：急性胰腺炎伴NOMI异常严重。如果血浆CPK和乳酸水平非常高，则应怀疑NOMI。

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