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Health-related quality of life and burden of disease in chronic pain measured with the 15D instrument

机译：使用15D仪器测量的与健康相关的生活质量和慢性疼痛的疾病负担

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Health-related quality of life (HRQoL) measurement aims to capture the complete, subjective health state of the patients and to comprehensively evaluate treatment outcomes. The aim of this study was to assess, using the 15D HRQoL instrument, HRQoL in a sample of 1528 chronic pain patients, referred to the multidisciplinary pain clinic of the Helsinki University Hospital during 2004 to 2012. The 15D results of the chronic pain patients were compared with those of a matched general population. To analyse the properties of the 15D, the results were compared with the preadmission questionnaire of the pain clinic, containing questions about background factors, aspects of the pain, and its impact on life. The mean 15D score of the chronic pain patients was one of the lowest reported using 15D; 0.710 vs 0.922 in the general population. It equalled the score of advanced cancer patients in palliative care. The 15D scores were normally distributed, and 15D showed both statistically and clinically significant discriminative power in pain-related background factors. Visual analogue scale on pain intensity, visual analogue scale on pain-related distress, and the impact of pain on daily life correlated well with the 15D score. Pain intensity did not have independent predictive value on the score. The results indicate heavy perceived burden of illness in chronic pain patients. In light of the questions analysed, 15D appears sensitive and discriminative in chronic pain patients in tertiary care. Instead of pain intensity, the impaired HRQoL in chronic pain was mainly because of the psychosocial aspects of pain.
机译：与健康相关的生活质量（HRQoL）测量旨在捕获患者的完整，主观健康状况，并全面评估治疗结果。这项研究的目的是使用15D HRQoL仪器评估1528名慢性疼痛患者的样本中的HRQoL，该样本在2004年至2012年间转诊至赫尔辛基大学医院的多学科疼痛诊所。慢性疼痛患者的15D结果为与匹配的一般人群相比。为了分析15D的特性，将结果与疼痛诊所的入院前问卷进行了比较，其中包含有关背景因素，疼痛方面及其对生活的影响的问题。慢性疼痛患者的平均15D评分是使用15D报告的最低评分之一;总人口比重为0.710和0.922。它等于姑息治疗中晚期癌症患者的分数。 15D评分呈正态分布，而15D评分在疼痛相关背景因素中具有统计学和临床​​上的显着判别力。 15D评分与视觉模拟量表有关疼痛强度，视觉模拟量表有关疼痛相关困扰以及疼痛对日常生活的影响密切相关。疼痛强度对评分没有独立的预测价值。结果表明，在慢性疼痛患者中感觉到沉重的疾病负担。根据已分析的问题，在三级护理的慢性疼痛患者中，15D显得敏感而有区别。代替疼痛强度，慢性疼痛中的HRQoL受损主要是由于疼痛的社会心理方面。

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