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首页> 外文期刊>Pain. >Self-reported somatosensory symptoms of neuropathic pain in fibromyalgia and chronic widespread pain correlate with tender point count and pressure-pain thresholds.
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Self-reported somatosensory symptoms of neuropathic pain in fibromyalgia and chronic widespread pain correlate with tender point count and pressure-pain thresholds.

机译：自我报告的纤维肌痛和慢性广泛性疼痛中的神经性疼痛的体感症状与压痛点数和压痛阈值相关。

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摘要

Widespread pain and pain hypersensitivity are the hallmark of fibromyalgia, a complex pain condition linked to central sensitization. In this study the painDETECT questionnaire (PDQ), validated to identify neuropathic pain and based on pain quality items, was applied in a cross-sectional sample of patients with chronic widespread pain (CWP). The aims of the study were to assess the patient-reported sensory neuropathic symptoms by PDQ and to correlate these with tender point (TP) count and pressure-pain thresholds. Eighty-one patients (75 F, 6 M) with CWP (ACR-criteria) filled in the PDQ. Manual TP examination was conducted according to ACR guidelines. Computerized cuff pressure algometry was used for the assessment of pressure-pain detection thresholds (PDT, unit: kPa) and pressure-pain tolerance thresholds (PTT, unit: kPa). Mean TP count was 14.32 (range: 2-18), mean PDQ score 22.75 (range: 5-37). Mean PDT was 8.8 kPa (range: 2-36) and mean PTT 30.9 kPa (range: 4-85). Deep-tissue hyperalgesia was the predominant somatosensory symptom reported in 83%, but other neuropathic symptoms were also frequent, e.g. burning 51% and prickling 47%. Statistically significant correlations were found between PDQ score and TP count: r=0.35 (p<0.01), and PDQ score and PDT: r=0.45 (p<0.01), and PTT: r=0.43 (p<0.01). The study indicates that pain in CWP has neuropathic features, and that the presence and number of tender points are associated with neuropathic pain symptoms. A high mean PDQ score was found to correlate with TP count and pressure-pain thresholds. The PDQ may become a useful tool assisting in the identification of central sensitization in patients with CWP and in the future diagnostic assessment fibromyalgia.
机译：广泛的疼痛和疼痛超敏反应是纤维肌痛的标志，纤维肌痛是与中枢敏化有关的复杂疼痛。在这项研究中，painDETECT问卷（PDQ）经过验证可识别神经性疼痛，并基于疼痛质量项目，被应用于慢性广泛性疼痛（CWP）患者的横断面样本中。该研究的目的是通过PDQ评估患者报告的感觉神经病性症状，并将其与压痛点（TP）计数和压痛阈值相关联。 PDQ中有81名CWP（ACR标准）患者（75 F，6 M）。根据ACR指南进行了手动TP检查。使用计算机化的袖带压力法用于评估压力疼痛检测阈值（PDT，单位：kPa）和压力疼痛耐受性阈值（PTT，单位：kPa）。平均TP计数为14.32（范围：2-18），平均PDQ得分为22.75（范围：5-37）。平均PDT为8.8 kPa（范围：2-36），平均PTT为30.9 kPa（范围：4-85）。深层组织痛觉过敏是主要的躯体感觉症状，占83％，但其他神经病理症状也很常见，例如燃烧51％，点刺47％。在PDQ评分和TP计数之间发现统计学上显着的相关性：r = 0.35（p <0.01），PDQ评分与PDT：r = 0.45（p <0.01）和PTT：r = 0.43（p <0.01）。研究表明，CWP中的疼痛具有神经性特征，并且压痛点的存在和数量与神经性疼痛症状有关。发现较高的平均PDQ得分与TP计数和压力痛阈值相关。 PDQ可能会成为有用的工具，有助于识别CWP患者的中枢致敏性，并在将来对纤维肌痛进行诊断评估。

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