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Schistosomiasis in infants and pre-school-aged children in sub-Saharan Africa: Implication for control

机译:撒哈拉以南非洲婴儿和学龄前儿童中的血吸虫病:控制的意义

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Until recently, the epidemiology and control of schistosomiasis in sub-Saharan Africa have focused primarily on infections in school-aged children and to a lesser extent on adults. Now there is growing evidence and reports of infection in infants and pre-school-aged children (≤6 years old) in Ghana, Kenya, Mali, Niger, Nigeria and Uganda, with reported prevalence from 14% to 86%. In this review, we provide available information on the epidemiology, transmission and control of schistosomiasis in this age group, generally not considered or included in national schistosomiasis control programmes that are being implemented in several sub-Saharan African countries. Contrary to previous assumptions, we show that schistosomiasis infection starts from early childhood in many endemic communities and factors associated with exposure of infants and pre-school-aged children to infection are yet to be determined. The development of morbidity early in childhood may contribute to long-term clinical impact and severity of schistosomiasis before they receive treatment. Consistently, these issues are overlooked in most schistosomiasis control programmes. It is, therefore, necessary to review current policy of schistosomiasis control programmes in sub-Saharan Africa to consider the treatment of infant and pre-school-aged children and the health education to mothers.
机译:直到最近,撒哈拉以南非洲的血吸虫病的流行病学和控制主要集中在学龄儿童的感染上,而成年人则较少。现在,在加纳,肯尼亚,马里,尼日尔,尼日利亚和乌干达,越来越多的证据和报告表明婴儿和学龄前儿童(≤6岁)受到感染,据报道患病率从14%上升到86%。在这篇综述中,我们提供了有关该年龄段血吸虫病的流行病学,传播和控制的可用信息,通常在撒哈拉以南非洲一些国家正在实施的国家血吸虫病控制计划中并未考虑或未包括这些信息。与以前的假设相反,我们表明血吸虫病感染始于许多流行社区的儿童早期,与婴儿和学龄前儿童接触感染相关的因素尚待确定。儿童期早期发病率的发展可能有助于血吸虫病在接受治疗之前的长期临床影响和严重性。一致地,这些问题在大多数血吸虫病控制计划中被忽略。因此,有必要审查撒哈拉以南非洲现行的血吸虫病控制方案政策,以考虑对婴儿和学龄前儿童的治疗以及对母亲的健康教育。

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