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Fostering informed decisions: A randomized controlled trial assessing the impact of a decision aid among men registered to undergo mass screening for prostate cancer

机译:促进知情决策:一项随机对照试验评估了决策辅助对注册进行前列腺癌大规模筛查的男性的影响

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Objective: Screening asymptomatic men for prostate cancer is controversial and informed decision making is recommended. Within two prostate cancer screening programs, we evaluated the impact of a print-based decision aid (DA) on decision-making outcomes. Methods: Men (. N=. 543) were 54.9 (SD. =. 8.1) years old and 61% were African-American. The 2(booklet type: DA vs. usual care (UC)). ×. 2(delivery mode: Home vs. Clinic) randomized controlled trial assessed decisional and screening outcomes at baseline, 2-months, and 13-months. Results: Intention-to-treat linear regression analyses using generalized estimating equations revealed that DA participants reported improved knowledge relative to UC (. B=. .41, p<. .05). For decisional conflict, per-protocol analyses revealed a group by time interaction (. B=. -.69, p<. .05), indicating that DA participants were less likely to report decisional conflict at 2-months compared to UC participants (OR. =. .49, 95% CI: .26-.91, p<. .05). Conclusion: This is the first randomized trial to evaluate a DA in the context of free mass screening, a challenging setting in which to make an informed decision. The DA was highly utilized by participants, improved knowledge and reduced decisional conflict. Practice implications: These results are valuable in understanding ways to improve the decisions of men who seek screening and can be easily implemented within many settings.
机译:目的:筛查无症状男性前列腺癌是有争议的,建议做出明智的决策。在两个前列腺癌筛查计划中,我们评估了基于打印的决策辅助(DA)对决策结果的影响。方法:男性(。N =。543)为54.9(SD。=。8.1)岁,61%为非裔美国人。 2(小册子类型:DA与常规护理(UC))。 ×。 2(分娩方式:家庭与临床)随机对照试验评估了基线,2个月和13个月时的决策和筛查结果。结果:使用广义估计方程进行的意向治疗线性回归分析显示,DA参与者报告了相对于UC的知识有所提高(。B = .41,p <.05)。对于决策冲突,按协议进行的分析显示了按时间交互作用的组(。B =。-.69,p <.05),表明与UC参与者相比,DA参与者在2个月内报告决策冲突的可能性较小( OR。= 0.49,95%CI:.26-.91,p <.05)。结论:这是第一项在免费质量筛查的背景下评估DA的随机试验,这是一项难以做出明智决定的挑战。参与者充分利用了发展议程,提高了知识水平并减少了决策冲突。实践意义:这些结果对于理解改善寻求筛查的男性的决策的方法非常有价值,并且可以在许多环境中轻松实施。

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