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Pseudotumor Cerebri Secondary to Subacute Sclerosing Panencephalitis.

机译:伪肿瘤性脑继发于亚急性硬化性全脑炎。

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摘要

Unusual presentations are not rare in subacute sclerosing panencephalitis. Five patients initially diagnosed with pseudotumor cerebri were ultimately determined to have pseudotumor cerebri secondary to subacute sclerosing panencephalitis. The present study retrospectively reviewed 56 cases history, neurologic symptoms, and clinical and laboratory data, as well as the outcomes. On admission, five patients (group 1) presenting with pseudotumor cerebri exhibited bilateral papilledema, and in each of them cranial magnetic resonance imaging revealed small lateral ventricles, effacement of the subarachnoid space, and no mass lesion. On admission, 51 patients (group 2) had no pseudotumor cerebri findings. The year of original measles infection, the interval between measles and onset of subacute sclerosing panencephalitis, and initial neurologic symptoms were similar, but length of symptoms before diagnosis of subacute sclerosing panencephalitis was shorter in group 1, and the clinical stage of subacute sclerosing panencephalitis on admission was more advanced in group 2. Cerebrospinal fluid mean open pressure was 378 +/- 22 H(2)O in group 1 and 146 +/- 28 H(2)O in group 2; cerebrospinal fluid antibody was 2038 +/- 768 U/L in group 1 and was 664 +/- 214 U/L in group 2. Only three of the five patients with pseudotumor cerebri had typical periodic discharges on electroencephalographic examination. These findings suggest that subacute sclerosing panencephalitis can cause pseudotumor cerebri.
机译:在亚急性硬化性全脑炎中,异常表现并不罕见。最初被确诊为假肿瘤性脑的五名患者最终被确定为继发于亚急性硬化性全脑炎的假肿瘤性脑。本研究回顾性回顾了56例病史,神经系统症状,临床和实验室数据以及结局。入院时,出现假性脑的5例患者(第1组)表现出双侧乳头水肿,并且每例患者的颅骨磁共振成像均显示侧脑室小,蛛网膜下腔消失,无肿块病变。入院时,有51名患者(第2组)未发现假性肿瘤脑。第一组在最初的麻疹感染年份,麻疹与亚急性硬化性全脑炎发作之间的间隔和最初的神经系统症状相似,但在诊断亚急性硬化性全脑炎之前症状的长度较短,并且亚急性硬化性全脑炎的临床分期在第2组的入院率更高。第1组的脑脊液平均开放压力为378 +/- 22 H(2)O,第2组为146 +/- 28 H(2)O。第一组脑脊液抗体为2038 +/- 768 U / L,第二组为664 +/- 214 U / L。在五例假肿瘤脑患者中,只有三例在脑电图检查中具有典型的周期性放电。这些发现表明亚急性硬化性全脑炎可引起假性肿瘤脑。

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