Cerebral white matter fractional anisotropy and tract volume as measured by MR imaging are associated with impaired cognitive and motor function in pediatric posterior fossa tumor survivors

Rueckriegel Stefan M.; Bruhn Harald; Thomale Ulrich W.; Driever Pablo Hernaiz

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Cerebral white matter fractional anisotropy and tract volume as measured by MR imaging are associated with impaired cognitive and motor function in pediatric posterior fossa tumor survivors

机译：MR成像测量的脑白质分数各向异性和尿道容积与小儿后颅窝肿瘤幸存者的认知和运动功能受损有关

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BackgroundDisease and therapy cause brain damage and subsequent functional loss in pediatric patients with posterior fossa tumors. Treatment-related toxicity factors are resection in patients with pilocytic astrocytoma (PA) and, additionally, cranio-spinal irradiation together with chemotherapy in patients with medulloblastoma (MB). We tested whether damage to white matter (WM) as revealed by diffusion tensor MR imaging (DTI) correlated with specific cognitive and motor impairments in survivors of pediatric posterior fossa tumors.

机译：背景疾病和治疗在患有后颅窝肿瘤的小儿患者中引起脑损伤和随后的功能丧失。与治疗相关的毒性因子是对毛细胞母细胞瘤（PA）的患者进行切除，此外，对髓母细胞瘤（MB）的患者进行颅脊髓照射联合化疗。我们测试了弥散张量MR成像（DTI）揭示的对白质（WM）的损伤是否与小儿后颅窝肿瘤幸存者的特定认知和运动障碍相关。

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《Pediatric blood & cancer》 |2015年第7期|共7页
作者
Rueckriegel Stefan M.; Bruhn Harald; Thomale Ulrich W.; Driever Pablo Hernaiz;
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正文语种 eng
中图分类儿科学;
关键词
diffusion tensor imaging; DTI; pediatric brain tumors; white matter integrity;

机译：弥散张量成像;DTI;小儿脑肿瘤;白质完整性;

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1. Cerebral white matter fractional anisotropy and tract volume as measured by MR imaging are associated with impaired cognitive and motor function in pediatric posterior fossa tumor survivors [J] . Rueckriegel Stefan M., Bruhn Harald, Thomale Ulrich W., Pediatric blood & cancer . 2015,第7期

机译：MR成像测量的脑白质分数各向异性和尿道容积与小儿后颅窝肿瘤幸存者的认知和运动功能受损有关
2. Cerebral white matter fractional anisotropy and tract volume as measured by MR imaging are associated with impaired cognitive and motor function in pediatric posterior fossa tumor survivors [J] . Rueckriegel Stefan M., Bruhn Harald, Thomale Ulrich W., Pediatric blood & cancer . 2015,第7期

机译：MR成像测量的脑白质分数各向异性和尿道容积与小儿后颅窝肿瘤幸存者的认知和运动功能受损有关
3. Could Single White Matter Tracts Tell Us Something about Long-Term Executive and Motor Functioning of Survivors of Childhood Posterior Fossa Tumors? [J] . Sleurs C., Nollet K., Gillebert C., Pediatric blood & cancer . 2019,第S4期

机译：单身白质子可以告诉我们一些关于儿童后窝肿瘤的幸存者的长期执行和运动功能吗？
4. Regional white matter volume and the relation with attentional functioning in survivors of malignant pediatric brain tumors [C] . John O. Glass, Raymond K. Mulhern, Holly A. White, Conference on Physiology and Function: Methods, Systems, and Applications Feb 16-18, 2003 San Diego, California, USA . 2003

机译：恶性小儿脑肿瘤幸存者的区域白质量及其与注意功能的关系
5. White Matter Microstructure and Emotional Functioning in Children Treated for Posterior Fossa Tumours [D] . Moxon-Emre, Iska. 2019

机译：后窝肿瘤治疗儿童的白质微观结构和情绪功能
6. White Matter Fractional Anisotropy Is a Superior Predictor for Cognitive Impairment Than Brain Volumes in Older Adults With Confluent White Matter Hyperintensities [O] . Yi Xing, Jianwei Yang, Aihong Zhou, 2021

机译：白质分数各向异性是一种优越的预测因子用于认知障碍而不是老年成年人的脑量损伤融合白质超收缩
7. Physical functioning in pediatric survivors of childhood posterior fossa brain tumors [O] . P. J. Piscione, E. Bouffet, D. J. Mabbott, 2013

机译：儿童后后肢体脑肿瘤儿科幸存者的身体作用

Cerebral white matter fractional anisotropy and tract volume as measured by MR imaging are associated with impaired cognitive and motor function in pediatric posterior fossa tumor survivors

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