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首页> 外文期刊>Pediatric neurology >Brainstem lesions in children with perinatal brain injury.
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Brainstem lesions in children with perinatal brain injury.

机译：围产期脑损伤患儿脑干病变。

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摘要

Several distributive patterns of hypoxic-ischemic cerebral injury have been recognized in asphyxiated newborns. Lesions of the brainstem have been rarely noted on magnetic resonance images in previous reports because they are difficult to detect. In this study, we demonstrate subtle but definite uniform symmetric brainstem lesions in children with perinatal brain injury. The areas of abnormal intensity were judged to comprise the central tegmental tract. The clinical manifestations in our patients were less severe than those previously described in patients with brainstem lesions. Two patients had difficulty of eye movement, but otherwise had no significant symptoms of brainstem cranial nerve nuclei involvement. All patients had lesions of white matter or cortex. Therefore, the abnormality in the dorsal brainstem revealed by magnetic resonance images is possibly as a result of secondary degeneration of the neurons that send axons into that tract.
机译：窒息新生儿已发现了几种缺氧缺血性脑损伤的分布模式。在以前的报道中，很少在磁共振图像上注意到脑干病变，因为它们很难被发现。在这项研究中，我们证明了围产期脑损伤儿童的微妙但确定的均匀对称性脑干病变。强度异常的区域被判断为构成中央被膜束。我们患者的临床表现不如先前描述的脑干病变患者严重。两名患者的眼球运动困难，但没有明显的脑干颅神经核受累症状。所有患者均有白质或皮质病变。因此，磁共振图像显示的背侧脑干异常可能是由于将轴突送入该区域的神经元继发性变性所致。

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