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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Suicidal Behavior Differs Among Early and Late Adolescents Treated With Antidepressant Agents
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Suicidal Behavior Differs Among Early and Late Adolescents Treated With Antidepressant Agents

机译：抗抑郁药治疗的青少年早期和晚期自杀行为有所不同

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OBJECTIVE: To identify circumstances and characteristics of suicidal behavior among early (aged 10-14 years) and late (aged 15-18 years) adolescents from a cohort of youth who were prescribed antidepressant medication. METHODS; In-depth reviews of all available medical records were performed for 250 randomly chosen confirmed episodes of suicidal behavior identified as part of a large retrospective cohort study of antidepressant users and suicidal behavior. Study data were obtained from Tennessee Medicaid records and death certificates from January 1, 1995, to December 31, 2006. Medical records and autopsy reports for cases identified from electronic data were adjudicated by 2 investigators blinded to exposure status and classified by using a validated scale. RESULTS: Of the 250 cases reviewed, 65.6% were female and 26.4% were aged 10 to 14 years. Medication ingestion was the most frequent method of suicidal behavior for both early and late adolescents; however, early adolescents were significantly more likely to use hanging as a method of suicide. Nearly one-half of the adolescents had previously attempted suicide. Early adolescents were significantly more likely to have a history of sexual abuse and significantly less likely to have a history of substance abuse. Early adolescents were also significantly more likely than older adolescents to have a history of a psychotic disorder and to report hallucinations before the suicide attempt.CONCLUSION: Suicidal behavior among early and late adolescents prescribed antidepressant medication differed in terms of methods used, previous psychiatric history, and proximal symptoms.
机译：目的：确定一组接受抗抑郁药物治疗的青年早期（10-14岁）和晚期（15-18岁）青少年的自杀行为情况和特征。方法;对所有250项随机选择的已确认的自杀行为发作进行了所有可用医学记录的深入审查，这些发作被确定为抗抑郁药使用者和自杀行为的大型回顾性队列研究的一部分。研究数据来自1995年1月1日至2006年12月31日的田纳西州医疗补助记录和死亡证明。由电子数据识别的病例的医疗记录和尸检报告由两名不愿透露其接触状况的调查员进行裁决，并使用经过验证的量表进行分类。结果：在所审查的250例病例中，女性占65.6％，年龄10至14岁的占26.4％。药物摄入是青少年早期和晚期青少年最常见的自杀行为方法。但是，早期青少年使用挂饰自杀的可能性要高得多。以前有将近一半的青少年曾尝试自杀。早期青少年有性虐待史的可能性大大增加，而有药物滥用史的可能性也大大降低。结论：早期和晚期青少年服用抗抑郁药的自杀行为在所用方法，既往精神病史，和近端症状。

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