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NICU practices and outcomes associated with 9 years of quality improvement collaboratives.

机译:与9年质量改进合作相关的NICU实践和成果。

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OBJECTIVE: Quality improvement collaboratives (QICs) can improve short-term outcomes, but few have examined their long-term results. This study evaluated the changes in treatment practices and outcomes associated with participation in multiple sequential QICs. DESIGN AND METHODS: This retrospective, 9-year, pre-post study of very low birth weight infants, we assessed treatment and outcomes from the 8 NICUs of the Reduce Lung Injury (ReLI) group of a QIC sponsored by the Vermont Oxford Network (VON). We analyzed data from 1998 (pre-ReLI), 2001 (last ReLI year), and 2006 (5 years after ReLI) by using univariate and multiple regression. RESULTS: A total of 4065 very low birth weight infants were treated in ReLI NICUs in 1998, 2001, and 2006. From 1998 to 2006, the ReLI group decreased delivery room intubation (70% vs 52%; adjusted odds ratio [aOR]: 0.2 [95% confidence interval (CI): 0.2-0.3]; P < .001), conventional ventilation (75% vs 62%; aOR: 0.3 [95% CI: 0.2-0.4]; P < .001), and postnatal steroids for BPD (35% vs 10%; aOR: 0.09 [95% CI: 0.07-0.1]; P < .001). They increased the use of nasal continuous positive airway pressure (57% vs 78%; aOR: 3.3 [95% CI: 2.7-3.9]; P < .001). BPD-free survival remained unchanged (68% vs 66%; aOR: 0.9 [95% CI: 0.7-1.1]; P = .16), the BPD rate increased (25% vs 29%; aOR: 1.3 [95% CI: 1.1-1.6]; P = .017), survival to discharge increased (90% vs 93%; aOR: 1.5 [95% CI: 1.1-2.2]; P < .001), and nosocomial infections decreased (18% vs 15%; aOR: 0.8 [95% CI: 0.6-0.99]; P = .045). CONCLUSIONS: Participation in VON-sponsored QICs was associated with sustained implementation of potentially better respiratory practices, increased survival, and reduced nosocomial infections. The BPD-free survival rate did not change, and the BPD rate increased. Implemented changes endured for at least 5 years after the QIC.
机译:目的:质量改进合作组织(QIC)可以改善短期结果,但很少有人检查其长期结果。这项研究评估了参与多个顺序QIC的治疗方法和结局的变化。设计与方法:这项对极低出生体重婴儿进行的为期9年的回顾性前期研究,我们评估了由佛蒙特州牛津网络(QF)赞助的QIC的8例减少肺损伤(ReLI)组的重症监护病房(NICU)的治疗和结果。冯)。我们使用单变量和多元回归分析了1998年(ReLI之前),2001年(ReLI最近的年份)和2006年(ReLI之后的5年)的数据。结果:1998年,2001年和2006年,共计4065例极低出生体重的婴儿在ReLI NICU中接受了治疗。从1998年至2006年,ReLI组减少了分娩室插管(70%比52%;调整后的优势比[aOR]: 0.2 [95%置信区间(CI):0.2-0.3]; P <.001),常规通气(75%vs 62%; aOR:0.3 [95%CI:0.2-0.4]; P <.001)和BPD的产后类固醇(35%vs 10%; aOR:0.09 [95%CI:0.07-0.1]; P <.001)。他们增加了鼻腔持续气道正压的使用(57%比78%; aOR:3.3 [95%CI:2.7-3.9]; P <.001)。无BPD生存率保持不变(68%vs 66%; aOR:0.9 [95%CI:0.7-1.1]; P = .16),BPD发生率增加(25%vs 29%; aOR:1.3 [95%CI :1.1-1.6]; P = .017),出院生存期增加(90%比93%; aOR:1.5 [95%CI:1.1-2.2]; P <.001),医院感染减少(18%vs。 15%; aOR:0.8 [95%CI:0.6-0.99]; P = .045)。结论:参加VON赞助的QIC与持续实施可能更好的呼吸习惯,增加生存率和减少医院感染有关。无BPD的存活率没有变化,而BPD的比率却增加了。 QIC之后,实施的变更至少持续了5年。

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