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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Internet-based reporting to the vaccine adverse event reporting system: a more timely and complete way for providers to support vaccine safety.
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Internet-based reporting to the vaccine adverse event reporting system: a more timely and complete way for providers to support vaccine safety.

机译：基于互联网的疫苗不良事件报告系统报告：提供者支持疫苗安全性的更及时，更完整的方法。

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BACKGROUND: On March 22, 2002, Internet-based reports (IBRs) were added to the Vaccine Adverse Event Reporting System (VAERS) to allow rapid, expedited reporting of adverse events (AEs) in anticipation of wider use of counter-bioterrorism vaccines such as those against smallpox and anthrax. OBJECTIVES: To evaluate the impact of IBRs on the timeliness and completeness of vaccine AE reporting. METHODS: To evaluate timeliness and completeness, we compared the proportions of IBRs with non-Internet-based reports (NIBRs). Report interval was analyzed for timeliness and age at vaccination, birth date, and onset date for report completeness. To evaluate the impact of the smallpox vaccination program, we compared smallpox vaccine reports separately. Because influenza vaccine is the most widely used vaccine in adults each year, we compared influenza vaccine reports separately. RESULTS: During the study period, VAERS received 54 364 NIBRs (85.8%) and 9008 IBRs (14.2%). Sixteen percent (1455) of IBRs followed smallpox vaccination. Overall, for all vaccines and for smallpox vaccine alone, IBRs had a greater proportion of completeness and a shorter report interval. The proportion of most frequently reported AEs did not differ between IBRs and NIBRs. A higher proportion of adults (18-64 years old) who received influenza vaccine chose to complete an IBR (62% vs 48%). CONCLUSIONS: The improved timeliness and completeness of IBRs allow VAERS to more rapidly detect new or rare vaccine AEs. This important advantage is critical in times of increased public concern about vaccine safety. Clinical vaccine providers should be aware of VAERS and use IBRs whenever feasible to report vaccine AEs.
机译：背景：2002年3月22日，基于互联网的报告（IBR）被添加到疫苗不良事件报告系统（VAERS）中，以便迅速，迅速地报告不良事件（AE），以期预期将广泛使用反生物恐怖主义疫苗，例如就像那些对抗天花和炭疽的人一样。目的：评估IBRs对疫苗不良事件报告及时性和完整性的影响。方法：为了评估及时性和完整性，我们将IBR与非基于Internet的报告（NIBR）的比例进行了比较。分析报告间隔的疫苗接种时效性和年龄，出生日期和发病日期，以确保报告完整性。为了评估天花疫苗接种计划的影响，我们分别比较了天花疫苗报告。因为流感疫苗是每年成人中使用最广泛的疫苗，所以我们分别比较了流感疫苗的报告。结果：在研究期间，VAERS接收了54364个NIBR（占85.8％）和9008个IBR（占14.2％）。百分之十六（1455）的IBR接种了天花疫苗。总体而言，对于所有疫苗和单独的天花疫苗，IBR的完整率更高，报告间隔更短。 IBR和NIBR之间，最常报告的AE的比例没有差异。接受流感疫苗的成年人（18-64岁）比例较高，他们选择完成IBR（62％对48％）。结论：IBR的及时性和完整性得到改善，使得VAERS能够更快地检测出新的或罕见的疫苗AE。在公众日益关注疫苗安全性时，这一重要优势至关重要。临床疫苗提供者应了解VAERS，并在可行的情况下使用IBR报告疫苗不良事件。

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