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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Estimating the effectiveness of screening for scoliosis: a case-control study.
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Estimating the effectiveness of screening for scoliosis: a case-control study.

机译：评估脊柱侧弯筛查的有效性：一项病例对照研究。

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OBJECTIVE: The aim of this study was to test the hypothesis that screening for scoliosis is effective in reducing the need for surgical treatment. METHODS: The study was a case-control study. A total of 125 consecutive patients who were treated surgically for idiopathic scoliosis between January 2001 and October 2004 and who were born on or after January 1, 1984, were invited; 108 agreed to participate. A total of 216 control subjects were selected randomly and anonymously, matched with respect to age and gender. For 279 adolescents, exact screening exposure and outcomes could be analyzed. Case subjects were recruited from 4 university and 6 nonuniversity Dutch hospitals; control subjects were recruited from all 37 municipal health services in The Netherlands. RESULTS: Screen-detected patients received diagnoses at a significantly younger age than did otherwise-detected patients (10.8 +/- 2.6 vs 13.4 +/- 1.7 years). In total, 32.8% of the surgically treated patients had been screened between 11 and 14 years of age, compared with 43.4% of the control subjects. The odds ratio for being exposed to screening was 0.64. In total, 28% of the patients were diagnosed as having scoliosis before 11 years of age. CONCLUSIONS: Our results showed no evidence that screening for scoliosis reduced the need for surgery. Abolishing screening seems justified, especially because the effectiveness of early treatment with bracing is still strongly debated. A randomized, controlled trial on the effectiveness of treating patients with idiopathic scoliosis with bracing is urgently needed.
机译：目的：本研究的目的是检验以下假设：对脊柱侧弯进行筛查可有效减少手术治疗的需求。方法：该研究为病例对照研究。总共邀请了在2001年1月至2004年10月之间接受手术治疗的特发性脊柱侧弯的连续患者125例，这些患者于1984年1月1日或之后出生。 108名同意参加。根据年龄和性别，共随机选择了216名对照对象。对于279名青少年，可以分析确切的筛查暴露和结果。病例受试者来自4所大学和6所荷兰大学医院;从荷兰的所有37个市政卫生机构中招募了控制对象。结果：筛查发现的患者比其他疾病发现的患者显着更年轻（10.8 +/- 2.6 vs 13.4 +/- 1.7岁）。在11至14岁之间接受筛查的手术患者总数为32.8％，而对照组为43.4％。暴露于筛查的比值比是0.64。总共有28％的患者在11岁之前被诊断出患有脊柱侧弯。结论：我们的结果没有证据表明筛查脊柱侧弯可以减少手术需求。取消筛查似乎是有道理的，尤其是因为仍在激烈地争论使用支架的早期治疗的有效性。迫切需要一项随机对照试验，以支架治疗特发性脊柱侧凸患者的有效性。

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