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Respiratory support in preterm infants at birth

机译:出生时早产儿的呼吸支持

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摘要

Current practice guidelines recommend administration of surfactant at or soon after birth in preterm infants with respiratory distress syndrome. However, recent multicenter randomized controlled trials indicate that early use of continuous positive airway pressure with subsequent selective surfactant administration in extremely preterm infants results in lower rates of bronchopulmonary dysplasia/death when compared with treatment with prophylactic or early surfactant therapy. Continuous positive airway pressure started at or soon after birth with subsequent selective surfactant administration may be considered as an alternative to routine intubation with prophylactic or early surfactant administration in preterm infants.
机译:当前的实践指南建议在患有呼吸窘迫综合征的早产儿出生时或出生后不久使用表面活性剂。但是,最近的多中心随机对照试验表明,与预防性或早期表面活性剂治疗相比,在极早产儿中早期使用持续的气道正压通气并随后选择性地给予表面活性剂可导致较低的支气管肺发育不良/死亡率。在早产儿或出生后不久开始连续持续的气道正压,随后进行选择性的表面活性剂给药,可以被视为早产儿预防性或早期表面活性剂常规插管的替代方法。

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